Associate Director, Skeletal Diseases
Apply NowCompany: Switch4 LLC
Location: Petaluma, CA 94954
Description:
Job Title: Musculoskeletal Therapeutic Area In Vivo Lead, Associate Director
Location: Petaluma, CA
Job-Type: Full Time/Permanent
Job Summary:
Seeking for a highly motivated and agile Associate Director with experience in skeletal biology and disease to join the team as the Musculoskeletal Therapeutic (MSK) Area In Vivo Lead. The Associate Director will manage the portfolio of in vivo MSK studies across the Therapeutic Area as well as manage a team of in vivo staff focused on developing therapeutics for musculoskeletal diseases.
Responsibilities:
Study Project Management:
Effectively collaborate with both internal and external scientists on completion of musculoskeletal therapeutic area in vivo studies which includes CRO study placement/monitoring.
Managing in vivo study projects including study design, sizing of cohorts, dosing, application of in vivo testing modalities, tissue collection, sample management, animal model selection, data analysis including statistics application, authoring study reports, and interpretation/presentation of scientific results.
Provide projection on study project needs including budgeting, staffing, and scheduling.
lign in vivo team priorities with the priorities of the MSK TA and Research.
Execute hands-on responsibilities including, but not limited to animal handling and restraint (rodents), administration via various routes of administration, including intravenous (tail-vein), in-life animal health monitoring and measurements, clinical observations, sample collection and processing, and accurate data collection. In addition, providing daily care and monitoring of mice or rats, including health checks and documentation, will also be required.
Effectively collaborate with other in vivo leads from other therapeutic areas to ensure portfolio project study prioritization. This includes working with other units to share equipment and staffing as needed.
Follow all institutional, local, and federal regulations regarding animal care and use. Adhere to safety protocols and maintain a clean and organized work environment. Maintain detailed and accurate records of all procedures and animal health status including adverse study events. Meticulous electronic lab notebook documentation.
With minimal guidance, collect, analyze, interpret, and present data within the Musculoskeletal Therapeutic group and across functional areas within the company.
Communicate experimental plans and results to the leadership team. Support product development and regulatory filings for pivotal clinical studies.
Follow instructions and work independently to effectively manage time and prioritize tasks to ensure all assignments are completed on or before deadlines.
Must have excellent troubleshooting, organization, and planning skills, and the ability to work under timeline in a fast-paced environment.
Excellent written and oral communication skills to effectively share scientific findings.
Excellent documentation skills including maintenance of daily records using Electronic Lab Notebooks and generation/maintenance of technical procedure documents and SOPs.
Willingness to work on site full time including off hours and weekends based on study needs.
Other duties as assigned.
General requirements for the position:
Demonstrated experience in skeletal biology/disease or muscular biology/disease research in academia or industry (preferred) including publication record.
Strong analytical, problem-solving, and decision-making skills.
Strong understanding of genetically engineered models, breeding, and management and Gene therapy modalities.
Excellent oral and written communication skills.
Passion for contributing your scientific skills to develop therapies for patients in need.
Must be able to utilize computer databases for analysis, data entry, and point of care observations.
Must be able to work under time constraints with minimal direction of day-to-day responsibilities, including collaboratively working with multidisciplinary teams.
Must be able to regularly read, understand, verify accuracy, and document various written of protocols, including Animal Care and Use Protocols and Standard Operating Procedures.
Must be able to work with external regulatory agencies and accreditation groups.
Some "off-core business hours" work required.
Complete all company training requirements.
Perform all work per designated safety standards and comply with Personal Protective
Equipment requirements and occupational health to perform work tasks.
This position is an on-site critical required position.
Other duties as assigned.
Education and Experience Requirements:
PhD in a related subject area with demonstrated research experience in skeletal biology.
Postdoctoral or previous industry experience in skeletal biology (7+years)
Extensive hands-on experience with rodent in vivo work.
Previous in vivo staff management experience.
Location: Petaluma, CA
Job-Type: Full Time/Permanent
Job Summary:
Seeking for a highly motivated and agile Associate Director with experience in skeletal biology and disease to join the team as the Musculoskeletal Therapeutic (MSK) Area In Vivo Lead. The Associate Director will manage the portfolio of in vivo MSK studies across the Therapeutic Area as well as manage a team of in vivo staff focused on developing therapeutics for musculoskeletal diseases.
Responsibilities:
Study Project Management:
Effectively collaborate with both internal and external scientists on completion of musculoskeletal therapeutic area in vivo studies which includes CRO study placement/monitoring.
Managing in vivo study projects including study design, sizing of cohorts, dosing, application of in vivo testing modalities, tissue collection, sample management, animal model selection, data analysis including statistics application, authoring study reports, and interpretation/presentation of scientific results.
Provide projection on study project needs including budgeting, staffing, and scheduling.
lign in vivo team priorities with the priorities of the MSK TA and Research.
Execute hands-on responsibilities including, but not limited to animal handling and restraint (rodents), administration via various routes of administration, including intravenous (tail-vein), in-life animal health monitoring and measurements, clinical observations, sample collection and processing, and accurate data collection. In addition, providing daily care and monitoring of mice or rats, including health checks and documentation, will also be required.
Effectively collaborate with other in vivo leads from other therapeutic areas to ensure portfolio project study prioritization. This includes working with other units to share equipment and staffing as needed.
Follow all institutional, local, and federal regulations regarding animal care and use. Adhere to safety protocols and maintain a clean and organized work environment. Maintain detailed and accurate records of all procedures and animal health status including adverse study events. Meticulous electronic lab notebook documentation.
With minimal guidance, collect, analyze, interpret, and present data within the Musculoskeletal Therapeutic group and across functional areas within the company.
Communicate experimental plans and results to the leadership team. Support product development and regulatory filings for pivotal clinical studies.
Follow instructions and work independently to effectively manage time and prioritize tasks to ensure all assignments are completed on or before deadlines.
Must have excellent troubleshooting, organization, and planning skills, and the ability to work under timeline in a fast-paced environment.
Excellent written and oral communication skills to effectively share scientific findings.
Excellent documentation skills including maintenance of daily records using Electronic Lab Notebooks and generation/maintenance of technical procedure documents and SOPs.
Willingness to work on site full time including off hours and weekends based on study needs.
Other duties as assigned.
General requirements for the position:
Demonstrated experience in skeletal biology/disease or muscular biology/disease research in academia or industry (preferred) including publication record.
Strong analytical, problem-solving, and decision-making skills.
Strong understanding of genetically engineered models, breeding, and management and Gene therapy modalities.
Excellent oral and written communication skills.
Passion for contributing your scientific skills to develop therapies for patients in need.
Must be able to utilize computer databases for analysis, data entry, and point of care observations.
Must be able to work under time constraints with minimal direction of day-to-day responsibilities, including collaboratively working with multidisciplinary teams.
Must be able to regularly read, understand, verify accuracy, and document various written of protocols, including Animal Care and Use Protocols and Standard Operating Procedures.
Must be able to work with external regulatory agencies and accreditation groups.
Some "off-core business hours" work required.
Complete all company training requirements.
Perform all work per designated safety standards and comply with Personal Protective
Equipment requirements and occupational health to perform work tasks.
This position is an on-site critical required position.
Other duties as assigned.
Education and Experience Requirements:
PhD in a related subject area with demonstrated research experience in skeletal biology.
Postdoctoral or previous industry experience in skeletal biology (7+years)
Extensive hands-on experience with rodent in vivo work.
Previous in vivo staff management experience.