Data Scientist

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Company: Synectics Inc.

Location: Worcester, MA 01604

Description:

Responsibilities:
  • Seeking a talented and highly motivated Data Scientist to join our expanding Spatial omics team within the Discovery Immunology Pathology group.
  • Develop and apply computational methods for the analysis of image-based spatial omics datasets, including the integration of multi-modal omics data and data interpretation in order to derive novel biological insights, identify disease biomarkers and new therapeutic targets.
  • Will be part of a unique multidisciplinary team working closely with pathologists, image analysts, and research scientists across the organization in a highly dynamic and collaborative environment to support pathology driven spatial omics projects that contribute to innovative drug discovery research.
  • Design, develop and implement computational pipelines for processing and analyzing spatial omics datasets, including spatial transcriptomics and proteomics.
  • Collaborate with pathologists and image analysts to develop methods to integrate and analyze spatial transcriptomics data with other spatial modalities, such as IHC or mIF
  • Collaborate with pathologists to validate spatial analysis tools in the context of tissue structure to ensure accuracy and reproducibility
  • Ensure scalability and efficiency of the pipelines to handle large and complex datasets
  • Lead the development of data visualization tools to effectively communicate findings to both technical and non-technical stakeholders.
  • Stay current with emerging trends and technologies in spatial omics and bioinformatics and assess their applicability to ongoing projects.
  • Generate concise reports and accurately document project details, algorithms and results in electronic laboratory notebook

Qualifications :
  • Ph.D. (or equivalent experience) in Computational Biology, Bioinformatics, Systems Biology, or a related field.
  • Strong proficiency in programming languages such as Python, R, or MATLAB, and relevant data science libraries (such as NumPy, Pandas, Matplotlib, Scikit-learn, etc.) for data analysis, manipulation, and visualization.
  • Experience with bioinformatics tools and databases, especially those pertinent to omics data analysis (Seurat, Scanpy, Squidpy)
  • Excellent analytical, problem-solving, and communication skills.
  • Ability to work independently and as part of a team, managing multiple projects simultaneously.
  • Experience developing analysis solutions for single-cell transcriptomics, or mIF proteomics datasets

Preferred Qualifications:
  • Familiarity with digital pathology image analysis platforms (Visopharm and Qupath) and spatial omics analytic platforms (BioTuring)
  • Experience with machine learning frameworks and data visualization tools.
  • Familiarity with cloud-based (AWS) and high-performance computing environments
  • Background in life sciences or experience in the pharmaceutical industry preferred.
  • Experience with tissue-based image analysis and immunologic diseases is preferred

Benefits:

Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.

Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.

Vision Insurance : Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.

Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.

Synectics is an equal opportunity employer.

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