Faculty Position - Gene Therapy

Overview:

The primary mission of the Jerry R. Mendell Center for Gene Therapy in the Abigail Wexner Research Institute at Nationwide Children's Hospital is to develop novel genetically based therapies for inherited diseases in order to ease the burden of these diseases on children and their families.

This mission is pursued by a dedicated team of laboratory scientists whose work is directed toward clinical applications, and by the efforts of clinician-scientists who are tasked with bringing these therapies into clinical trials. More information is available at:

Center for Gene Therapy (nationwidechildrens.org)

About the Faculty Position:

• Seeking Assistant, Associate, or Full Professor (Tenure Track at The Ohio State University College of Medicine)
• Candidates should have a research laboratory focused on neuromuscular, neurological, or neurodegenerative diseases relevant to gene therapies
• Will establish an independent research program
• Will help develop and accelerate novel gene therapies to the clinic

Qualifications Required:

• MD, MD/PhD, or PhD
• Strong track record of publishing in high quality journals
• Current K-award, R01 or equivalent grant funding is strongly preferred.

About the Center:

• The center is interested in all aspects of gene therapy, including but not limited to gene replacement, gene editing, immunological issues associated with gene therapy, and the development and production of AAV and other vector systems.
• Faculty in the center are supported by access to affiliated pre-clinical and GMP clinical vector production facilities, a robust Office of Technology Commercialization, a highly experienced clinical trials infrastructure, and a world-class genomics core specializing in next-generation sequencing. In-house expertise in regulatory affairs, including IND development and submission, is provided through the Office of Research Regulatory Affairs
• Principal Investigators are also Faculty members at The Ohio State University College of Medicine

For more information about the position, contact Kevin Flanigan, MD, Director of the Jerry R. Mendell Center for Gene Therapy at Kevin.Flanigan@nationwidechildrens.org. Send correspondence, including curriculum vitae, a brief statement of research interests, and contact information for three references to Patrick.Kennedy@nationwidechildrens.orgin Faculty Recruitment.

Job Description Summary:

Designs experiment and develop protocols required to conduct meaningful research in a specific area of scientific research. Trains and guides technical staff involved in specific projects and performing techniques. Plans future directions and seeks sources of funding for a research group. Records, collects, and analyzes data from research studies, and publishes results in appropriate refereed scientific journals. Presents study results to Research Institute (RI) staff as well as at national scientific conferences. Collaborates with other RI investigators in a manner that will enrich the overall institutional research effort. Prepares for seeking and obtaining external research funding. Serves as a mentor to RI post-doctoral research fellows (Research Scientists).

Job Description:

Essential Functions:

• Designs experiments and develops protocols necessary to conduct meaningful research in a specific scientific area. Does "hands-on" performance of techniques as needed to complete projects. Ensures that research projects are conducted efficiently, correctly, and in a timely manner.
• Trains subordinate research staff such as technicians, graduate students, post-doctoral fellows, etc. so that they can perform techniques required for conducting the studies.
• Records, collects, and analyzes study data to be able to reach valid conclusions. With the results in mind, plans for future research directions and studies.
• When study data has been analyzed statistically, prepares papers and publishes results in appropriate scientific journals. Presents results and conclusions to scientists at the weekly CRI research meetings and at national conferences.
• Collaborates with other RI and OSU investigators to mutually benefit research efforts. Serves as a resource in a particular area of scientific expertise.
• Provides mentorship to graduate students and post-doctoral fellows (Research Scientists) in preparing them to be independent researchers.
• Performs appropriate duties as a member of the faculty of the Ohio State University College of Medicine.
• Prepares scientific proposals to seek external research funding whenever possible.
• Prepares and monitors capital budget for the area of responsibility. Responsible for authorizing expenditures from approved grant funds.
• Recruits, hires, terminates and trains assigned staff. Trains staff for compliance to hospital policies, RI, NIH, NRC, AALAC requirements and OSHA standards and regulations. Also conducts training on animal care and use as appropriate.

Education Requirement:
Ph.D. or MD/Ph.D. or equivalent degree and having completed a post-doctoral fellowship in a pertinent area of scientific expertise.

Licensure Requirement:
(not specified)

Certifications:
(not specified)

Skills:

• Good communication skills, and ability to prepare scientific publications, presentations and proposals.
• Technical skills in an appropriate area of research.
• Ability to teach and train junior scientists.
• Desire to pursue a career in biomedical research, and knowledge of the research process.

Experience:
(not specified)

Physical Requirements:
OCCASIONALLY: (none specified)

FREQUENTLY: (none specified)

CONTINUOUSLY: (none specified)

Additional Physical Requirements performed but not listed above:
Pressure in this position will vary depending on the workload. The workload will be heavy but manageable most of the time. Pressure may arise in the face of deadlines associated with grants, required documentation related to the physician's OSU faculty appointment, etc.

Business Analytics - Working Knowledge (Meets Expectations), Emotional Intelligence - Extensive Experience (Meets Expectations), NCH Core Values - Basic Understanding (Meets Expectations), Organizational Savvy and Politics - Extensive Experience (Meets Expectations), PhD, Self-Directed Growth and Development - Extensive Experience (Meets Expectations), Workforce Diversity Management - Extensive Experience (Meets Expectations)

"The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individuals so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under their supervision. EOE M/F/Disability/Vet"