Founder & CEO - Oncology Biotech

Founder & CEO - Oncology Biotech (ADC/Cancer Stem Cell Therapy)
Location: U.S. or Europe | Type: Co-founder Opportunity

A preclinical biotech venture is seeking a Founder & CEO to lead development of a first-in-class protein drug conjugate (PDC) targeting cancer stem cells (CSCs)-a critical driver of metastasis, recurrence, and drug resistance.

The technology, based on natural ligands of LGR4/5/6 receptors, has shown strong anti-tumor activity in preclinical models of colorectal, ovarian, and gastric cancer. Backed by a prominent research foundation and supported by an experienced inventor, the company is poised for IND-enabling studies and first-in-human trials.

Responsibilities:

• Drive both dilutive and non-dilutive fundraising
• Shape clinical and regulatory strategy
• Oversee preclinical and IND-enabling activities
• Build partnerships with CROs, CDMOs, pharma, and KOLs
• Lead the company through early clinical development

Ideal Profile:

• Proven experience in biotech fundraising and leadership
• Background in ADC or biologics development
• Strong oncology network and scientific credibility
• Familiarity with early-stage clinical and regulatory milestones

The Opportunity:

• Equity-based co-founder role
• Compensation tied to successful fundraising
• Access to infrastructure and support from a broader venture-building ecosystem

This is a rare opportunity to lead a scientifically differentiated oncology company from inception through early clinical development.