Histology Research Associate

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What You Will Contribute To Altos

The Research Associate/ Senior RA candidate should have extensive experience in histology sample preparation for IHC, IF, and ISH staining and imaging modalities. The Research Associate will play a key role in expanding the capabilities and capacity of histology operations to advance larger R&D initiatives.

Responsibilities

• Provide robust and reproducible histology sample preparation including tissue processing, embedding, sectioning, and histological staining - (human and animal frozen and FFPE tissues and cell culture/organoids)
• Develop, qualify, and apply specialized assay protocols, including immunohistochemistry, in situ hybridization, and immunoflourescence assays to support research objectives
• Independent operation of specialized equipment, including sectioning equipment and auto-stainers, and troubleshooting when issues occur.
• Oversee sample tracking, data entry, and data management within the group.
• Qualify and quantify control existing assay and staining methods
• Work with the team lead and vendors to upgrade, customize and maintain instrumentation
• Maintain specimen inventories and laboratory records
• Assist with creating and optimizing SOPs and technical training materials
• Assist with new user trainings

Who You Are

Minimum Qualifications

• Previous experience in a biological/medical/pharmaceutical research setting
• At least 5 years of relevant experience
• Competency with tissue preparation, grossing, and embedding. Have advanced microtomy skills (cryo and paraffin cutting) and extensive experience staining (H&E, special stains and IHC).
• Experience working with various tissues and a proven ability to troubleshoot difficult tissues.
• Experience supporting scientists within a team or core environment.
• Capable of managing lab projects and ability to clearly follow instructions, keeping to timelines and agreed outcomes.
• Have an ability to perform experiments acutely and reproducibly.
• Be an excellent team player and be excited about collaborating.
• Strong communication skills, with proven ability to work as part of a diverse team.
• Ability to multitask and work across projects and groups with flexibility to react to changing priorities
• Meticulous attention to detail.

Preferred Qualifications

• BS or MS in Biology or related field
• Histotechnology Certification
• Experience with digital image analysis
• Prior experience in advanced techniques e.g. RNAscope and/or spatial omics
• Previous work with bone, skin, liver, lung, and/or muscle samples.
• Previous work with human tissue.
• High level of computer literacy and ability to maintain an electronic lab notebook
• Experience working within in a centralized scientific resource facility

The salary range for San Diego, CA:

Research Associate II: $89,760 - $117,300

Senior Research Associate: $103,840 - $135,700

Exact compensation may vary based on skills, experience, and location.

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What We Want You To Know

We are a culture of collaboration and scientific excellence, and we believe in the values of inclusion and belonging to inspire innovation.

Altos Labs provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Altos currently requires all employees to be fully vaccinated against COVID-19, subject to legally required exemptions (e.g., due to a medical condition or sincerely-held religious belief).

Thank you for your interest in Altos Labs where we strive for a culture of scientific excellence, learning, and belonging.

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