Principal Associate Scientist, Gene Therapy
Apply NowCompany: Nature Careers
Location: Cambridge, MA 02139
Description:
Job Description
- Work independently and with cross-functional teams to perform and develop molecular assays to characterize in vivo AAV vector performance.
- Plan and execute molecular analysis on animal tissues, including DNA/RNA isolation, RT, qPCR, and NGS library preparation.
- Participate in process optimization independently or under limited supervision.
- Develop in-depth knowledge in the gene therapy field.
- Be a critical thinker familiar with the recent advancement in the focused research area and contribute to the team decision-making process.
- Maintain complete, accurate, and timely electronic records to support internal documentation needs and regulatory submissions.
- Manage time efficiently and contribute to multiple projects under demanding timelines.
- Summarize results across multiple experiments in clear presentations to colleagues on the team.
- Extensive hands-on experience in molecular biology techniques, including DNA/RNA isolation from animal tissues, RT, qPCR, DNA gel electrophoresis, SDS-PAGE, WB.
- Extensive hands-on experience in NGS library preparation.
- Proficiency with analytical and presentation software, including Powerpoint, Excel, and Graphpad.
- Excellent oral and written communication skills.
- Works with colleagues as a team player.
- Strong organizational and time management skills, able to advance multiple projects in parallel.
- Proficiency in aseptic cell culture techniques.
- Ability to design plasmid constructs and perform molecular cloning of these constructs.