Research Fellow

Every Cure is a start-up, nonprofit drug development organization on a mission to alleviate suffering for the ~300 million people worldwide battling diseases without FDA-approved treatments by unlocking hidden cures. We are building a first-of-its-kind, AI-powered platform to identify FDA-approved treatments that can be repurposed for untreated diseases. Inspired by our success in repurposing over a dozen drugs for new uses, including one that is saving Dr. David Fajgenbaum's own life, we are committed to unlocking the full potential of FDA-approved drugs to treat every disease and patient possible.

Our groundbreaking approach revolves around building an open-source database and employing cutting-edge tools to identify drug repurposing opportunities. Since launching at the 2022 Clinton Global Initiative, we have received tremendous media attention and recognition including the 2023 Elevate Prize Foundation Founder's Award, attracted leaders from across industries, been invited to share about our work at the White House, Aspen Ideas, and a Congressional Caucus Briefing, and demonstrated the life-saving potential of our platform.

Four strategic pillars guide our efforts:

• Using an AI engine to identify promising drug repurposing opportunities.
• Prioritizing high-impact opportunities which affect neglected patient communities.
• Efficiently validating promising opportunities through laboratory and clinical studies.
• Ensuring everyone has equitable access to new cures.

As a nonprofit organization, we can focus on maximizing patient impact and saving lives without needing to consider the commercial viability of drugs, including the 80% that are already generic and completely neglected. Our team, comprising experts in drug discovery, data analysis, and clinical trials, collaborates with entities ranging from philanthropic organizations to biopharmaceutical industries including Chan Zuckerberg Initiative, Flagship Pioneering, Clinton Global Initiative, Elevate Prize Foundation, and Lyda Hill Philanthropies, among others.

The Every Cure team is expanding rapidly and seeking top-notch, purpose-driven professionals to perform a range of tasks to save lives with hidden cures. This is a unique opportunity to join a highly motivated, patient-focused team that works closely with international collaborators, government agencies, academic researchers, philanthropic organizations, and biopharmaceutical companies to make a significant impact on patients with major unmet medical needs.

The Research Fellow will play a crucial role in advancing potential treatments for various rare and non-rare diseases. This positional involves integrating all available data into biomedical knowledge graphs, applying AI algorithms to these datasets, and investigating promising treatment approaches to evaluate in clinical trials. The Research Fellow will report directly to the Chief Medical Officer of Every Cure and collaborate with Data Scientists, Data Engineers, and Tech Translators to conceptualize and develop study plans and perform targeted analyses.

The role demands both independent and collaborative work to advance the strategic scientific direction of our initiative targeting rare diseases. The Research Fellow will interface broadly with internal and external stakeholders to achieve the goal of accelerating the identification of effective treatments for rare diseases.

How you will make an impact:

• Integrate data into biomedical knowledge graphs and apply AI algorithms for analysis.
• Investigate and evaluate promising treatment approaches for clinical trials.
• Develop and execute study plans and perform targeted analyses.
• Collaborate with internal teams and external partners to advance research objectives.
• Recruit, train, supervise, and mentor team members, graduate students, fellows, and scientific collaborators.
• Support the mission of Every Cure through direct scientific leadership and collaboration.
• Communicate effectively with team members and stakeholders to ensure successful project outcomes.
• Publish research findings in peer-reviewed journals and present at scientific conferences.
• Stay updated with the latest research and developments in rare diseases and related fields.
• Develop grant proposals and contribute to fundraising efforts.
• Provide expertise and guidance on experimental design, data interpretation, and best practices.
• Facilitate knowledge transfer and training sessions for team members and collaborators.

What you will bring to the team:

• Education: PhD or MD in biomedical sciences or a related field.
• Experience: 3-5 years of relevant academic and/or work experience.
• Expertise in research planning and direct scientific leadership.
• Advanced understanding of computational analyses.
• Familiarity with rare diseases, immunology, and drug repurposing.
• Technical Skills:
  • Experience with database development and computational analyses.
  • Proficiency in AI analytic approaches is desirable.
  • Ability to interpret computational analyses of biomedical data.
  • Familiarity with experiments on cell lines and animal models.
  • Experience with real-world data interpretation.
  • Strong computer/technology skills, including database management, MS Excel, PowerPoint, and MS Project (or similar project management tools).
• Other Skills:
  • Strong desire to contribute and work collaboratively to achieve goals.
  • Ability to work independently with critical thinking and sound judgment.
  • Leadership skills in a multidisciplinary team.
  • Excellent oral and written communication skills with exceptional attention to detail.
• Personal Attributes:
  • Passionate about Every Cure's mission and values.
  • Highly organized and detail-oriented.
  • Adaptable and able to thrive in a fast-paced, dynamic environment.
  • Strong commitment to ethical standards and integrity.

Work Location:

This role will be based in Boston, MA.

Salary Range and Benefits:

$100,000 - $120,000 depending on experience, plus benefits including:

• Time Away from Work
• Paid Family/Medical Leave
• Holidays
• Health Insurance/Retirement Benefits