Research Scientist/Engineer 2

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Company: University of Washington

Location: Seattle, WA 98115

Description:

As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem-solving skills and dedication to build stronger minds and a healthier world.

UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits and natural beauty.

The Department of Pharmacology currently has an outstanding opportunity for a Research Scientist/Engineer 2.

Under the general direction of the PI, this position provides comprehensive research to develop novel bioassays to validate potential protein targets for drug development, and for the evaluation of potential disease modifying agents using in vitro bioassays as well as in vivo in the study of breast cancer and Cushing's syndrome.

DUTIES AND RESPONSIBILITIES

60% - In vitro and In vivo work:

  • Perform molecular biology techniques (i.e. PCR, DNA isolation/sequencing), mammalian cell culture, protein biochemistry and pharmacological cell signaling assays.
  • Identify and evaluate the roles of novel compounds for regulating in vitro phenotypes using modern cell signaling assays.
  • Contribute to the design and execution of cell and tissue-based studies to investigate biological mechanisms of breast cancer and Cushings syndrome.
  • Supervise management of mouse colony.
  • Prepare experimental reagents.
    20% - Data analysis and presentation:
  • Keep detailed records.
  • Analyze and interpret data.
  • Perform regular presentations of data to the research group.
    15% - Administrative:
  • Become aware of lab safety procedure.
  • Write and update IACUC protocols for experiments.
  • Liaison for regulatory agencies including IACUC and DEA.
  • Perform budget management including tracking and forecasting.
    5% - Training:
  • Training and directing other lab members including RSEs, graduate and undergraduate students.
    MINIMUM REQUIREMENTS
  • Bachelor of Science degree in Biology, Biochemistry, Molecular Biology or related field.
  • Minimum two years experience or an equivalent education and experience.
    ADDITIONAL REQUIREMENTS
  • Experience performing Cell and/or tissue-based studies including migration and proliferation assays.
  • In vivo experience using mouse disease models.
  • Experience with management of mouse colonies.
  • Experience performing molecular biology techniques.
    DESIRED QUALIFICATIONS
  • Experience performing protein biochemistry techniques.
  • Experience with lentiviral mammalian gene expression vectors.
  • Experience with Microscopy.
  • Must be able to learn budget management including tracking and forecasting.
    Application Process: The application process may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select "Apply to this position". Once you begin an assessment, it must be completed at that time; if you do not complete the assessment, you will be prompted to do so the next time you access your "My Jobs" page. If you select to take it later, it will appear on your "My Jobs" page to take when you are access ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
    Committed to attracting and retaining a diverse staff, the University of Washington will honor your experiences, perspectives and unique identity. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable and welcoming.
    The University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.
    To request disability accommodation in the application process, contact the Disability Services Office at [redacted] or [redacted].
    Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law.
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