Scientist, Genome Engineering
Apply NowCompany: Colossal Biosciences
Location: Dallas, TX 75217
Description:
An affiliate of Colossal is seeking a Scientist to provide their talent, knowledge, and passion for ambitious synthetic biology projects involving non-model organisms. The role requires working on a diverse set of workflows that involve precise genome manipulation. The candidate will work with a talented group of engineers and biologists committed to optimizing and developing novel technologies for large-scale editing of genomes.
This position will be based out of Dallas, TX. Relocation assistance is available.
Duties and Responsibilities:
Required Skills and Abilities:
Preferred Experience:
Education and Experience:
What Colossal Offers You:
The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That's why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices.
Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we're doing something big. Something Colossal.
Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.
EEO is the Law
Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house.
Colossal is proud to be named a Best Place to Work by BuiltIn for 3 years in a row across multiple categories in 2023, 2024, and 2025:
Built In 2025 Award Lists
Great Place to Work Certification Page
Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.
Newsweek's Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces!
This position will be based out of Dallas, TX. Relocation assistance is available.
Duties and Responsibilities:
- Build genome-editing workflows
- Design, innovate and iterate DNA assembly, integration, screening and functional assays
- Work on project milestones
- Attend lab meetings, prepare reports and presentations on the progress of projects
- Great organizational skills and excellent laboratory record maintenance
Required Skills and Abilities:
- Expertise with a variety of genome editing tools (CRISPR and more)
- Strong experience with mammalian cell culture systems
- Experience in molecular biology (PCR, nucleic and protein extraction, gel electrophoresis) and cloning techniques (restriction enzyme-based cloning, Gibson assembly, yeast assembly)
- Strong written and oral communication skills, as well as creative problem-solving skills
- Enjoys the fast-paced startup environment and teamwork
- Ability to function well in a growth-oriented, nimble environment.
Preferred Experience:
- Postdoctoral/industry work in gene editing, cell selection and cell screening
- Experience with large scale DNA assemblies
- Experience with NGS analysis workflows
- Peer-reviewed work on genome engineering in mammalian cell systems
Education and Experience:
- PhD in synthetic biology, biological sciences, bioengineering, molecular biology, genetics or related field.
- 3+ years hands-on expertise designing and cloning DNA constructs
- Applicants must be authorized to work in the U.S. without the need for any future sponsorship.
What Colossal Offers You:
- Medical, dental, and vision coverage
- Unlimited PTO and company holidays so you can rest and recharge
- Flexible spending accounts (FSA)
- Company matched 401k retirement plan
- Paid parental leave up to 12 weeks
- Education reimbursement
- An opportunity to help us return the Earth to a healthier state
The team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That's why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices.
Through it all, however, we maintain a culture of positivity, hope, happiness and belief that we're doing something big. Something Colossal.
Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.
EEO is the Law
Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house.
Colossal is proud to be named a Best Place to Work by BuiltIn for 3 years in a row across multiple categories in 2023, 2024, and 2025:
- #1 on the 50 Best Startups to Work For in Dallas in 2023!
- 100 Best Midsize Places to Work in Dallas in 2024 & 2025
- 100 Best Places to Work in Dallas, TX (All Size Employers) in 2024 & 2025
- 100 Best Midsize Places to Work in Boston in 2024 & 2025
Built In 2025 Award Lists
Great Place to Work Certification Page
Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.
Newsweek's Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces!