Scientist - Immune Cell Engineering Platform (Biohub NY)

The Chan Zuckerberg Biohub New York (CZ Biohub NY) (https://www.czbiohub.org/ny/) is an independent nonprofit research institute that brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine. CZ Biohub NY itself supports some of the brightest, boldest engineers, data scientists, and biomedical researchers to investigate the fundamental mechanisms underlying disease and develop new technologies that will lead to actionable diagnostics and effective therapies. We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all.

Our Vision

• We pursue large scientific challenges that cannot be pursued in conventional environments
• We enable individual investigators to pursue their riskiest and most innovative ideas
• The technologies developed at CZ Biohub facilitate research by scientists and clinicians at our home institutions and beyond

Diversity of thought, ideas, and perspectives are at the heart of CZ Biohub Network and enable disruptive innovation and scholarly excellence. We are committed to cultivating an inclusive organization where all colleagues feel inspired and know their work makes an important contribution.

The Opportunity

The Immune Cell Engineering Platform is a state-of-the-art facility dedicated to the systematic generation and bioengineering of iPSC-derived immune cells. It offers specialized expertise and cutting-edge technologies to the Biohub community, driving forward the scientific mission of CZ Biohub NY.

The Immune Cell Engineering Platform Lab is looking for a Scientist with expertise in iPSC biology and immune cell differentiation. The successful candidate will have a strong background in iPSC culture, differentiation to various immune cells (T-cells, NK-cells, Myeloid cells), experience with genome editing and assessment of immune function both in vitro and in vivo. The candidate is self-motivated, enthusiastic, independent and willing to with both internal and external laboratories.

What You'll Do

• Perform and optimize differentiation protocols of iPSC to various immune cells (T-cells, NK-cells, Myeloid cells)
• Design and perform in vitro and in vivo functional immune cell assessment
• Design and execute gene engineering strategies
• Establish and perform assays to assess immune cell identity and function
• Design, execute and analyze experiments
• Interpret and present experimental data (in both written and oral formats)
• Work closely with fellow team members and external partners
• Follow advances in the field through published literature and conferences

What You'll Bring

Essential -

• PhD in developmental biology or immunology
• 2 years expertise in culturing, characterizing and differentiating pluripotent stem cells
• Ability to design, plan and implement iPSC engineering and differentiation techniques
• 2 years expertise in molecular biology and biochemical techniques (including but not limited to CTL assays, flow cytometry, RNAseq, genome editing)
• Excellent communication skills (both verbal and written)
• Passionate and driven to advance the field
• Ability to collaborate in a diverse environment
• Ability to perform occasional weekend work when required

The Chan Zuckerberg Biohub Network requires all employees, regardless of work location or type of role, to provide proof of their initial COVID-19 vaccination by their start date. Those who are unable to get vaccinated because of a disability, or who choose not to be vaccinated due to a sincerely held religious belief, practice, or observance must have an approved exception prior to their start date.

Compensation

• Scientist I = $100,000 - $137,500
• Scientist II = $112,000 - $154,000

New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. To determine starting pay, we consider multiple job-related factors including a candidate's skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data. Your recruiter can share more about the specific pay range during the hiring process

What We Provide

• Resources to disrupt and innovate at the frontiers of our knowledge of biology and disease
• An environment where nothing is considered impossible, where bold and creative thinking are the norm, and where a collaborative culture allows teams of people from multiple disciplines to accomplish more than any single person can achieve alone
• Access to collaborators, resources and facilities at our three partner universities (Columbia University, The Rockefeller University, and Yale University) as well as partner organizations in the CZ Biohub Network and beyond
• Competitive compensation and benefits commensurate with experience

Benefits

We offer a robust benefits program that enables the important work Biohubbers do every day. Our benefits include healthcare coverage, life and disability insurance, commuter subsidies, family planning services with fertility care, childcare stipend, 401(k) match, flexible time off and a generous parental leave policy. In addition, we honor our commitment to career development and our value of scholarly excellence through regular onsite opportunities to learn from the world's leading scientists.

The CZ Biohub Network is an equal opportunity employer committed to diversity of thought, ideas, and perspectives. We are committed to cultivating an inclusive organization where all Biohubbers feel inspired and know their work makes an important contribution. Therefore, we provide employment opportunities without regard to age, race, color, ancestry, national origin, religion, disability, sex, gender identity or expression, sexual orientation, or any other protected status in accordance with applicable law.

Headhunters and recruitment agencies may not submit resumes/CVs through this Web site or directly to managers. The CZ Biohub Network does not accept unsolicited headhunter and agency resumes. The CZ Biohub Network will not pay fees to any third-party agency or company that does not have a signed agreement with the CZ Biohub Network.