Senior Scientist, RPD

AKTIS Oncology is a biotechnology company pioneering the discovery and development of a new class of targeted radiopharmaceuticals to treat a broad range of solid tumor cancers. Founded and incubated by MPM Capital with its seasoned team of entrepreneurs and drug developers, AKTIS has developed proprietary platforms to generate tumor-targeting agents with ideal properties for radiotherapy. Designed for high tumor penetration and long residence time, AKTIS Oncology's molecules can quickly clear other areas of the body, thereby maximizing tumor elimination while minimizing the side effects of treatment. These are therapies that would also enable clinicians to visualize and verify target engagement prior to exposure to therapeutic radioisotopes.

The Senior Scientist in the Radiopharmaceutical Development (RPD) team will be primarily responsible for the routine radiolabelling and analysis of AKTIS Oncology's proprietary radiopharmaceuticals in AKTIS' R&D laboratory in Boston. The Senior Scientist will also contribute to AKTIS Oncology's global radiopharmaceutical development and manufacturing program, including formulation development and stability testing. This individual will report to the Executive Director of Radiopharmaceutical Development and be an integral part of the CMC team contributing to the development of multiple portfolio programs. The position will collaborate closely with cross-functional team members to ensure the timely delivery of robust manufacturing and QC protocols. The position title will be finalized commensurate with experience and accomplishments. This role requires a full-time on-site presence.

BACKGROUND AND QUALIFICATIONS

• PhD in chemistry, biology, engineering, or related field
• 2+ years of experience in radiochemistry, including the use of radiometals is required
• Experience with radiotherapeutics is highly preferred
• Experience in the chemistry of peptides and small proteins is preferred
• Project management and organizational skills, and the ability to work independently and as a team member
• Strong desire to be part of a mission-oriented company leading transformative change for patients
• A combination of private and public company experience is preferred
• Proven demonstration of transparent communication and fostering open and diverse debate
• Ability to work with agility and manage ambiguity
• Personifies positive energy and exemplifies respect

ESSENTIAL DUTIES AND RESPONSIBILITIES

• Develop, optimize, and qualify radiolabelling and QC procedures for pre-clinical and early-phase clinical use
• Aid in the development of laboratory operational protocols and participate in day-to-day laboratory operations, including radiation safety
• Write development reports that can be used for transfer of technology
• Take on new challenges willingly and build a culture of rigor and data-driven decision-making to bring novel therapies to the clinic
• Demonstrate high standards for scientific rigor, team behaviors, excellence, and a culture of innovation that is fully aligned with company objectives