Site Director, Yale CryoEM Resource
Apply NowCompany: Yale University
Location: New Haven, CT 06511
Description:
Essential Duties
1. User Training: Develop novel training methodologies and train and mentor users of the research core, providing guidance and expertise.2. Experiment Support: Collaborate with interdisciplinary teams, faculty researchers, and external partners to address research challenges and drive innovation within the research core.3. Facility/Instrument Support: Lead and manage complex research projects within the research core, providing expert scientific guidance and oversight.4. Technique Development: Contribute to the development of research strategies and long-term planning for the research core and foster a culture of scientific excellence, mentorship, and professional development.5. Data Analysis/Interpretation: Provide thought leadership in the field and contribute to the advancement of scientific knowledge through collaborations and partnerships.6. Equipment Procurement: Lead the evaluation, acquisition, and maintenance of research core equipment.7. Professional Development: Stay updated with emerging research trends and technologies, driving innovation within the research core. Engage in scientific leadership activities, including leading new core initiatives and representing the research core at conferences and events.8. Scientific Participation: Actively participate in manuscript preparation and grant proposals, as applicable.9, Staff Training and Mentoring: Foster a culture of scientific excellence, mentorship, and professional development.10. Leadership: Collaborate with the university administration and faculty leadership on research core-related initiatives.11. Finance and Admin: Collaborate with the Core Director in the development and implementation of strategic plans and budgets for the research core.12. Vendor Relations: Shapes the overall vendor relations strategy, leads high-level negotiations, and collaborates with vendors on joint research initiatives.13. Education and Outreach: Lead education and outreach activities within the core, including tours, events, etc.
Required Education and Experience
Master's Degree in a related discipline and eight years of related experience or an equivalent combination of skills, education, and experience.
Background Check Requirements
All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks based on the position description and job requirements. All offers are contingent upon the successful completion of the background check. For additional information on the background check requirements and process visit "Learn about background checks" under the Applicant Support Resources section of Careers on the It's Your Yale website.
Position Focus:
The Yale CryoEM Resource (YCR) spans three sites: West Campus, Yale School of Medicine, and Science Hill, housing several advanced transmission electron microscopes to support applications from sample screening to single particle analysis and cryo-electron tomography. The research core also features advanced cryogenic sample preparation equipment and space for future expansion. The Site Director will provide strategic leadership, operational oversight, and scientific expertise for one of the three YCR sites. The Site Director will collaborate with researchers across Yale to drive technical advancements, support complex research initiatives, and foster a culture of innovation. The Site Director will play a key role in ensuring the highest standards of user support, training, and methodological development, strengthening Yale's cryo-EM capabilities for internal and external collaborations. The specific site assignment will be determined based on the qualifications of the candidate and institutional priorities.
Primary responsibilities include overseeing the day-to-day management and technical direction of the assigned YCR site, ensuring optimal performance of all facility instrumentation, and maintaining an environment that supports cutting-edge research. This includes minimizing equipment downtime, coordinating service and maintenance, managing service contracts, and implementing all necessary safety and security protocols. The Director will also work closely with researchers to provide expert guidance on experimental design, sample preparation, data acquisition, and computational image analysis, ensuring excellence in structure elucidation of biological macromolecules and complexes. In addition to facility operations, the Director will lead efforts to enhance cryo-EM methodologies, develop and implement best practices, and promote technical innovation in data collection and analysis. The Site Director will collaborate with users to promote technical innovation in cryo-EM data collection and analysis, organize and support cryo-EM workshops, and actively promote Yale's cryo-EM expertise within the broader scientific community. The role also involves supporting the YCR Managing Director by participating in user meetings, preparing equipment proposals, assisting in strategic planning, providing cross-coverage at other YCR sites and contributing to recruitment, training, and oversight of additional staff as needed.
Preferred Education, Experience and Skills:
Ph.D. or equivalent in biology, chemistry, physics, biophysics, structural biology or a closely related field and 10+ years of relevant experience.
Posting Disclaimer
The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties and responsibilities of the particular position. Employees will be assigned specific job-related duties through their hiring departments.
EEO Statement:
The University is committed to basing judgments concerning the admission, education, and employment of individuals upon their qualifications and abilities and seeks to attract to its faculty, staff, and student body qualified persons from a broad range of backgrounds and perspectives. In accordance with this policy and as delineated by federal and Connecticut law, Yale does not discriminate in admissions, educational programs, or employment against any individual on account of that individual's sex, sexual orientation, gender identity or expression, race, color, national or ethnic origin, religion, age, disability, status as a special disabled veteran, veteran of the Vietnam era or other covered veteran.
Inquiries concerning Yale's Policy Against Discrimination and Harassment may be referred to the Office of Institutional Equity and Accessibility (OIEA).
Required Skill/Ability 1:
Expertise in high-resolution structural analysis of macro-molecules using cryo-electron microscopy, including sample preparation and computational analysis with current (and self-written) software.
Required Skill/Ability 3:
High level competence in setting up, maintaining, and coordinating computational support for collection, storage, and analysis of cryo-EM datasets is crucial.
Required Skill/Ability 4:
Demonstrated experience in the use of current generation electron microscopes and direct electron detectors and interest in pursuing cutting-edge structural studies using cryo-EM, independently and with collaborators.
1. User Training: Develop novel training methodologies and train and mentor users of the research core, providing guidance and expertise.2. Experiment Support: Collaborate with interdisciplinary teams, faculty researchers, and external partners to address research challenges and drive innovation within the research core.3. Facility/Instrument Support: Lead and manage complex research projects within the research core, providing expert scientific guidance and oversight.4. Technique Development: Contribute to the development of research strategies and long-term planning for the research core and foster a culture of scientific excellence, mentorship, and professional development.5. Data Analysis/Interpretation: Provide thought leadership in the field and contribute to the advancement of scientific knowledge through collaborations and partnerships.6. Equipment Procurement: Lead the evaluation, acquisition, and maintenance of research core equipment.7. Professional Development: Stay updated with emerging research trends and technologies, driving innovation within the research core. Engage in scientific leadership activities, including leading new core initiatives and representing the research core at conferences and events.8. Scientific Participation: Actively participate in manuscript preparation and grant proposals, as applicable.9, Staff Training and Mentoring: Foster a culture of scientific excellence, mentorship, and professional development.10. Leadership: Collaborate with the university administration and faculty leadership on research core-related initiatives.11. Finance and Admin: Collaborate with the Core Director in the development and implementation of strategic plans and budgets for the research core.12. Vendor Relations: Shapes the overall vendor relations strategy, leads high-level negotiations, and collaborates with vendors on joint research initiatives.13. Education and Outreach: Lead education and outreach activities within the core, including tours, events, etc.
Required Education and Experience
Master's Degree in a related discipline and eight years of related experience or an equivalent combination of skills, education, and experience.
Background Check Requirements
All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks based on the position description and job requirements. All offers are contingent upon the successful completion of the background check. For additional information on the background check requirements and process visit "Learn about background checks" under the Applicant Support Resources section of Careers on the It's Your Yale website.
Position Focus:
The Yale CryoEM Resource (YCR) spans three sites: West Campus, Yale School of Medicine, and Science Hill, housing several advanced transmission electron microscopes to support applications from sample screening to single particle analysis and cryo-electron tomography. The research core also features advanced cryogenic sample preparation equipment and space for future expansion. The Site Director will provide strategic leadership, operational oversight, and scientific expertise for one of the three YCR sites. The Site Director will collaborate with researchers across Yale to drive technical advancements, support complex research initiatives, and foster a culture of innovation. The Site Director will play a key role in ensuring the highest standards of user support, training, and methodological development, strengthening Yale's cryo-EM capabilities for internal and external collaborations. The specific site assignment will be determined based on the qualifications of the candidate and institutional priorities.
Primary responsibilities include overseeing the day-to-day management and technical direction of the assigned YCR site, ensuring optimal performance of all facility instrumentation, and maintaining an environment that supports cutting-edge research. This includes minimizing equipment downtime, coordinating service and maintenance, managing service contracts, and implementing all necessary safety and security protocols. The Director will also work closely with researchers to provide expert guidance on experimental design, sample preparation, data acquisition, and computational image analysis, ensuring excellence in structure elucidation of biological macromolecules and complexes. In addition to facility operations, the Director will lead efforts to enhance cryo-EM methodologies, develop and implement best practices, and promote technical innovation in data collection and analysis. The Site Director will collaborate with users to promote technical innovation in cryo-EM data collection and analysis, organize and support cryo-EM workshops, and actively promote Yale's cryo-EM expertise within the broader scientific community. The role also involves supporting the YCR Managing Director by participating in user meetings, preparing equipment proposals, assisting in strategic planning, providing cross-coverage at other YCR sites and contributing to recruitment, training, and oversight of additional staff as needed.
Preferred Education, Experience and Skills:
Ph.D. or equivalent in biology, chemistry, physics, biophysics, structural biology or a closely related field and 10+ years of relevant experience.
Posting Disclaimer
The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties and responsibilities of the particular position. Employees will be assigned specific job-related duties through their hiring departments.
EEO Statement:
The University is committed to basing judgments concerning the admission, education, and employment of individuals upon their qualifications and abilities and seeks to attract to its faculty, staff, and student body qualified persons from a broad range of backgrounds and perspectives. In accordance with this policy and as delineated by federal and Connecticut law, Yale does not discriminate in admissions, educational programs, or employment against any individual on account of that individual's sex, sexual orientation, gender identity or expression, race, color, national or ethnic origin, religion, age, disability, status as a special disabled veteran, veteran of the Vietnam era or other covered veteran.
Inquiries concerning Yale's Policy Against Discrimination and Harassment may be referred to the Office of Institutional Equity and Accessibility (OIEA).
Required Skill/Ability 1:
Expertise in high-resolution structural analysis of macro-molecules using cryo-electron microscopy, including sample preparation and computational analysis with current (and self-written) software.
Required Skill/Ability 3:
High level competence in setting up, maintaining, and coordinating computational support for collection, storage, and analysis of cryo-EM datasets is crucial.
Required Skill/Ability 4:
Demonstrated experience in the use of current generation electron microscopes and direct electron detectors and interest in pursuing cutting-edge structural studies using cryo-EM, independently and with collaborators.