Scientist I, Process Development

About CTMC

CTMC is a pioneering biotech joint venture, formed by National Resilience and MD Anderson Cancer Center, and located in the renowned Texas Medical Center. Our mission is to accelerate cell therapies from bench to bedside. We offer a wide range of cell therapy modalities, including CAR-T, TIL, ETC, and TCR-T. Our expert team collaborates closely with MD Anderson's research and clinical faculty, bringing impactful cell therapies to cancer patients.

In our first year alone, we have filed four INDs, each ahead of schedule, demonstrating our commitment to delivering innovative treatments to patients with speed and precision. Our alliance with National Resilience, an ambitious biomanufacturing organization that has raised $2 billion in two years, enables us to remain at the forefront of biomanufacturing practices, leveraging advanced technology and processes to deliver exceptional results.

Our state-of-the-art, 60,000 sq. ft. facility in the Texas Medical Center is staffed by an integrated team of 93+ industry veterans and scientists who are passionate about bringing life-saving cures to patients. Our unique joint venture structure, with two highly established partners, provides us with the financial stability and long-term horizon to achieve our mission.

At CTMC, we value our employees and offer a variety of development opportunities within our novel corporate structure. We foster a team-first culture and a balanced work-life environment to ensure our staff is energized and engaged in our mission. If you share our passion for advancing the frontiers of medical science with innovative therapeutics and want to join a highly dedicated team committed to delivering novel cures to patients, we invite you to submit your application. We look forward to hearing from you and exploring how your skills and expertise can help us achieve our mission.

Responsibilities

• Play an important role in process development projects assigned by leadership with the goal to implement and improve CAR-T, TILs and other T-cell therapies.
• Participate in the design, plan and execution of the experimental plan on process development to streamline the production of T-cell products for cancer immunotherapy.
• Take part in developing processes in alignment with regulatory rules and procedures applying to the generation and quality monitoring of cell therapy products to ensure rapid translation of developed procedures in the GMP lab.
• Take initiatives of troubleshooting problems as they arise in the lab and share best practices and lessons learned with the team.
• Play an important role in providing technical assessment of various new cell therapy technologies and make recommendations on process decisions for GMP implementation.
• Execute project deliverables to meet timelines.
• Maintain current knowledge of the field and introduce relevant materials to continuously improve the current processes.
• Maintain thorough accurate, legible, and organized written records, and electronic records.
• Produce written protocols and reports. Prepare scientific presentations to report on the status of the work performed in the laboratory and speak in front of a group of scientists and management.
• Communicate effectively with lab members, manufacturing, analytical development and regulatory affairs.
• Interface with appropriate internal key stakeholders in partnerships
• Other duties as assigned.

Qualifications/Skills

• Ph.D. in a related scientific/engineering field preferred, or Masters degree with 5+ years' experience in a related field, preferably in the biotech industry or equivalent combination of education and experience.
• Experience in PD laboratory operations developing processes on various cell manufacturing platforms and closed systems for the development of T-cell therapy products.
• Strong knowledge in cell biology.
• Demonstrated ability to collaborate effectively in a multi-disciplinary team.
• Demonstrated strong communication skills, interpersonal skills and a superior drive for results.
• Excellent written, oral, interpersonal and presentation skills and the ability to effectively interface with senior management and staff.
• Excellent judgment and creative problem-solving skills, including negotiation and conflict resolution skills.
• Able to operate as an effective tactical, as well as strategic thinker.
• Able to coach and influence junior level scientists and associates.
• Able to work late nights, weekends, and holidays with very short advance notice.
• Proficient with Microsoft Office Suite or related software.

Working Conditions, Equipment, Physical Demands

The incumbent in this position works in an office environment. The incumbent in this position will use the following equipment and shall have the following physical demands:

Equipment-

• Computer, printer, fax, telephone, and laboratory testing equipment

Physical Demands-

• Occasional standing and walking required.
• Frequent sitting, reaching, and computer/keyboard usage.
• Occasional lifting, pushing, and pulling up to 10 lbs. required.

The physical demands and work environment that have been described are representative of those an employee encounters while performing the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions in accordance with the Americans with Disabilities Act.

The above job description is an overview of the functions and requirements for this position. This document is not intended to be an exhaustive list encompassing every duty and requirement of this position; your supervisor may assign other duties as considered necessary.