Group Leader - Immune Cell Organotropism and Adhesion (Biohub NY)

The Chan Zuckerberg Biohub New York (CZ Biohub NY) (https://www.czbiohub.org/ny/) is an independent nonprofit research institute that brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine. CZ Biohub NY itself supports some of the brightest, boldest engineers, data scientists, and biomedical researchers to investigate the fundamental mechanisms underlying disease and develop new technologies that will lead to actionable diagnostics and effective therapies. We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all.

Our Vision

• We pursue large scientific challenges that cannot be pursued in conventional environments
• We enable individual investigators to pursue their riskiest and most innovative ideas
• The technologies developed at CZ Biohub facilitate research by scientists and clinicians at our home institutions and beyond

Diversity of thought, ideas, and perspectives are at the heart of CZ Biohub Network and enable disruptive innovation and scholarly excellence. We are committed to cultivating an inclusive organization where all colleagues feel inspired and know their work makes an important contribution.

The Opportunity

CZ Biohub NY is looking to recruit an outstanding scientist for the position of Group Leader (equivalent to a Principal Investigator within the CZ Biohub Network) to lead our Immune Cell Organotropism and Adhesion research group.

As a Group Leader, you will be responsible for recruiting and overseeing an outstanding team of scientists dedicated to pioneering novel, influential studies to elucidate the role of cell adhesion in determining immune cell organotropism, with the ultimate goal of bioengineering immune cell trafficking to a specific organ/tissue of choice. Your research will align with the Biohub's mission to unravel the complexities of immune cell mechanisms and harness their functionalities to detect anomalies and diseases. Specific research areas of interest include programming immune cells to traffic to specific organs/tissues, designing synthetic receptors to enhance immune cell recognition of organ-specific physiologic and pathologic signals, creating co-culture organoid models to study cell-cell communication mechanisms in vitro, applying synthetic biology to further our understanding of tissue development principles, and exploring the mechanisms that govern immune cell interaction with other cells. The ultimate aim is to develop innovative technologies to engineer immune cell trafficking to specific organs on demand, paving the way for actionable diagnostics and effective therapies.

What You'll Do

• Lead and actively participate in an innovative, vigorous, and collaborative research program, aligned with the mission of CZ Biohub NY, dedicated to advancing the state of the art in understanding and modulating the trafficking of immune cells to specific organs, resulting in compelling record of scientific publication
• Play a key role in our collaborative efforts to engineer immune cells to detect, prevent, and cure organ-specific diseased states by leveraging your expertise in immune cell organotropism and cell adhesion mechanisms.
• Develop a transformative research vision and providing technical guidance and mentorship to team members
• Engage with colleagues throughout the Biohub to uphold our values of scholarly excellence, innovation, open communication, hands-on collaboration, partnership, and opportunity
• Communicate progress and results with colleagues and the leadership team
• Publish and disseminate impactful findings and the products of your research as preprints (medRxiv, bioRxiv) and/or software repositories (e.g., GitHub)
• Collaborate with the CZ Biohub team to patent and license technologies resulting from your research

What You'll Bring

Essential -

• PhD or MD with relevant research experience
• A minimum of 5 years post-doctoral experience focused on immune cell organotropism and adhesion
• Demonstrated publication track record in top tier journals on topics related to the scientific goals of this position
• Demonstrated leadership, track record of innovation, and ability to work collaboratively
• Supervisory or mentoring experience is a plus but not required for early-career applicants, but expected for more senior candidates
• Demonstrating a creative vision to establish a highly innovative and impactful research program
• Outstanding interpersonal and communication skills
• Demonstrated commitment to open science and highly aligned with the mission and values of CZ Biohub values

The Chan Zuckerberg Biohub Network requires all employees, regardless of work location or type of role, to provide proof of their initial COVID-19 vaccination by their start date. Those who are unable to get vaccinated because of a disability, or who choose not to be vaccinated due to a sincerely held religious belief, practice, or observance must have an approved exception prior to their start date.

Compensation

• $145,000 - $176,000

New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. To determine starting pay, we consider multiple job-related factors including a candidate's skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data. Your recruiter can share more about the specific pay range during the hiring process.

What We Provide

• Resources to disrupt and innovate at the frontiers of our knowledge of biology and disease
• An environment where nothing is considered impossible, where bold and creative thinking are the norm, and where a collaborative culture allows teams of people from multiple disciplines to accomplish more than any single person can achieve alone
• Access to collaborators, resources and facilities at our three partner universities (Columbia University, The Rockefeller University, and Yale University) as well as partner organizations in the CZ Biohub Network and beyond
• Competitive compensation and benefits commensurate with experience

Benefits

We offer a robust benefits program that enables the important work Biohubbers do every day. Our benefits include healthcare coverage, life and disability insurance, commuter subsidies, family planning services with fertility care, childcare stipend, 401(k) match, flexible time off and a generous parental leave policy. In addition, we honor our commitment to career development and our value of scholarly excellence through regular onsite opportunities to learn from the world's leading scientists.

The CZ Biohub Network is an equal opportunity employer committed to diversity of thought, ideas, and perspectives. We are committed to cultivating an inclusive organization where all Biohubbers feel inspired and know their work makes an important contribution. Therefore, we provide employment opportunities without regard to age, race, color, ancestry, national origin, religion, disability, sex, gender identity or expression, sexual orientation, or any other protected status in accordance with applicable law.

Headhunters and recruitment agencies may not submit resumes/CVs through this Web site or directly to managers. The CZ Biohub Network does not accept unsolicited headhunter and agency resumes. The CZ Biohub Network will not pay fees to any third-party agency or company that does not have a signed agreement with the CZ Biohub Network.