RESEARCH SCIENTIST/ENGINEER 4
Apply NowCompany: University of Washington
Location: Seattle, WA 98115
Description:
As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem-solving skills, and dedication to build stronger minds and a healthier world.
UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits, and natural beauty.
The Department of Laboratory Medicine and Pathology has an outstanding opportunity for a Research Scientist/Engineer 4 to join their team.
DUTIES AND RESPONSIBILITIES
The Research Scientist/Engineer 4 must develop original hypotheses and research plans and design novel experimental methods to achieve the specific research aims. Responsibilities include:
Scientific Research Activities (80%):
Manages multiple significant projects and makes substantial contributions to determining feasibility of goals and objectives.
Plans, schedules, conducts, and coordinates detailed phases of the work of major projects.
Independently performs most assignments with instructions as to the general results expected.
Possesses and applies a comprehensive knowledge of particular field of specialization to the completion of complex assignments.
Receives technical guidance on unusual or complex problems and supervisory approval on proposed plans for projects.
Identify possible novel project avenues.
Design, manage, and conduct experiments, analyze and interpret data, and communicate conclusions.
Write manuscripts about new research findings, assay development, and continuing data collection and interpretation.
Write individual grant proposals and assist in writing major grant proposals.
Participate in presentations to peers and supervisor both at formal conferences, lab meetings, and informal meetings with colleagues to share research findings and represent the UW research community.
Conduct literature reviews and background searches to determine optimal research methods, applicable cutting-edge techniques, and project planning.
Troubleshoot problems that arise in research protocols and report problems to the PI
Establish and maintain interdisciplinary collaborations to advance research project objectives by utilizing advanced analytical techniques.
Maintain detailed lab records.
Assist in writing and maintaining lab SOPs.
Perform other duties as assigned.
Supervisory Activities (15%):
Design, perform, assist, and train lab members in human monocyte cell culture, cell line maintenance, and directed differentiation into macrophages.
Design, perform and train lab members in in vitro bacterial infection models for defined outputs (macrophage bacterial ingestion and survival, macrophage fate, gene expression, protein production, serum survival).
Design, perform and train lab members in animal models of bacterial pathogenesis (planning, ordering, maintenance, infection, organ harvesting for defined measurable outputs, disposal).
Design, perform, assist and train lab members in basic molecular biology assays, such as RNA/protein extraction, RT-qPCR, western blotting, and plasmid design.
Design, perform, assist and train lab members in bacterial editing techniques to generate defined knockout mutants and allelic exchanges, and regulate gene expression.
Mentor staff and students to develop technical skills.
Other Duties (5%):
Inventory supplies and reagents.
General lab cleaning and maintenance.
Attend and participate in lab meetings and seminars.
MINIMUM REQUIREMENTS
Master's Degree in Microbiology AND four (4) years of related experience OR equivalent combination of education AND experience.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
ADDITIONAL REQUIREMENTS
Knowledge in bacterial genetics, cloning, mutagenesis, molecular methods for protein/nucleic acid/lipopolysaccharide analysis, tissue culture, phagocyte maturation, opsonization, serum survival, analysis of cell signaling pathways, complement activation, competitive virulence assays and transposon insertion sequencing in humanized mice.
DESIRED QUALIFICATIONS
Doctoral degree in microbiology
Microbiome analysis
Application Process: The application process may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select "Apply to this position". Once you begin an assessment, it must be completed at that time; if you do not complete the assessment, you will be prompted to do so the next time you access your "My Jobs" page. If you select to take it later, it will appear on your "My Jobs" page to take when you are access ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
REQUIREMENTS:
The Research Scientist/Engineer 4 (E S UAW RSE) in this role has primary responsibility for the oversight of an NIH-funded research project that examines pathogenic mechanisms of Salmonella Typhi and Salmonella Paratyphi A, the causative agents of enteric fever.
Committed to attracting and retaining a diverse staff, the University of Washington will honor your experiences, perspectives and unique identity. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable and welcoming.
The University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.
To request disability accommodation in the application process, contact the Disability Services Office at [redacted] or [redacted].
Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law.
UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits, and natural beauty.
The Department of Laboratory Medicine and Pathology has an outstanding opportunity for a Research Scientist/Engineer 4 to join their team.
DUTIES AND RESPONSIBILITIES
The Research Scientist/Engineer 4 must develop original hypotheses and research plans and design novel experimental methods to achieve the specific research aims. Responsibilities include:
Scientific Research Activities (80%):
Manages multiple significant projects and makes substantial contributions to determining feasibility of goals and objectives.
Plans, schedules, conducts, and coordinates detailed phases of the work of major projects.
Independently performs most assignments with instructions as to the general results expected.
Possesses and applies a comprehensive knowledge of particular field of specialization to the completion of complex assignments.
Receives technical guidance on unusual or complex problems and supervisory approval on proposed plans for projects.
Identify possible novel project avenues.
Design, manage, and conduct experiments, analyze and interpret data, and communicate conclusions.
Write manuscripts about new research findings, assay development, and continuing data collection and interpretation.
Write individual grant proposals and assist in writing major grant proposals.
Participate in presentations to peers and supervisor both at formal conferences, lab meetings, and informal meetings with colleagues to share research findings and represent the UW research community.
Conduct literature reviews and background searches to determine optimal research methods, applicable cutting-edge techniques, and project planning.
Troubleshoot problems that arise in research protocols and report problems to the PI
Establish and maintain interdisciplinary collaborations to advance research project objectives by utilizing advanced analytical techniques.
Maintain detailed lab records.
Assist in writing and maintaining lab SOPs.
Perform other duties as assigned.
Supervisory Activities (15%):
Design, perform, assist, and train lab members in human monocyte cell culture, cell line maintenance, and directed differentiation into macrophages.
Design, perform and train lab members in in vitro bacterial infection models for defined outputs (macrophage bacterial ingestion and survival, macrophage fate, gene expression, protein production, serum survival).
Design, perform and train lab members in animal models of bacterial pathogenesis (planning, ordering, maintenance, infection, organ harvesting for defined measurable outputs, disposal).
Design, perform, assist and train lab members in basic molecular biology assays, such as RNA/protein extraction, RT-qPCR, western blotting, and plasmid design.
Design, perform, assist and train lab members in bacterial editing techniques to generate defined knockout mutants and allelic exchanges, and regulate gene expression.
Mentor staff and students to develop technical skills.
Other Duties (5%):
Inventory supplies and reagents.
General lab cleaning and maintenance.
Attend and participate in lab meetings and seminars.
MINIMUM REQUIREMENTS
Master's Degree in Microbiology AND four (4) years of related experience OR equivalent combination of education AND experience.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
ADDITIONAL REQUIREMENTS
Knowledge in bacterial genetics, cloning, mutagenesis, molecular methods for protein/nucleic acid/lipopolysaccharide analysis, tissue culture, phagocyte maturation, opsonization, serum survival, analysis of cell signaling pathways, complement activation, competitive virulence assays and transposon insertion sequencing in humanized mice.
DESIRED QUALIFICATIONS
Doctoral degree in microbiology
Microbiome analysis
Application Process: The application process may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select "Apply to this position". Once you begin an assessment, it must be completed at that time; if you do not complete the assessment, you will be prompted to do so the next time you access your "My Jobs" page. If you select to take it later, it will appear on your "My Jobs" page to take when you are access ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
REQUIREMENTS:
The Research Scientist/Engineer 4 (E S UAW RSE) in this role has primary responsibility for the oversight of an NIH-funded research project that examines pathogenic mechanisms of Salmonella Typhi and Salmonella Paratyphi A, the causative agents of enteric fever.
Committed to attracting and retaining a diverse staff, the University of Washington will honor your experiences, perspectives and unique identity. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable and welcoming.
The University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.
To request disability accommodation in the application process, contact the Disability Services Office at [redacted] or [redacted].
Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law.