Scientist (Formulation)

Nextonic Solutions is seeking a highly ambitious, adaptable, structured, and detail-oriented Scientist to join our vibrant team at the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Vaccine Research Center (VRC), Vaccine Production Program (VPP).

Technical Requirements:

• Collaborate with a project team the evaluation and development of stable formulations in the liquid or frozen state (project dependent) for the vaccine candidates at VRC, including the following subtasks:
• Work with the Director of Formulation, Project Management, and Functional Leads from other process teams to develop a formulation development plan, including timeline, that is dictated by the specific product TPP and project requirements.
• Design fit-for-purpose formulation and stability studies.
• Oversee the technical execution of those studies, and personally execute studies as needed.
• Analyze, collate, and interpret study data (directly and that analyzed by team members) based on technical expertise, previous project experience, organization knowledge and accepted scientific field literature.
• Develop and execute assays for biological product characterization, formulation development and stability testing of recombinant protein-based vaccines, proteinaceous nanoparticles, and virus-like particles.
• Analyze, interpret, and present data in small group.
• Write and review technical reports and protocols documenting formulation, stability, and method development studies.
• Contribute directly to regulatory filings in collaboration with others.
• Provide strategic guidance and technical instruction, including in method and study deign theory.
• Work in collaboration with personnel to generate and complete professional development goals.
• Serve as Subject Matter Expert for one or more analytical and/or theoretical areas relevant to formulation development at the VRC.

Qualifications:

• Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, Chemical Engineering, or a related discipline.
• Industry, government or equivalent experience in protein or vaccine formulation, stability, characterization, or a related field (post-doctoral experience can apply).
• 8+ years combination industry, government, and/or academic experience in protein formulation and/or related fields.
• Strong knowledge of protein and/or polymer chemistry theory.
• Strong understanding of biophysical and bioanalytical properties of proteins and relevant analytical techniques.
• Strong experience with hands-on analysis and data interpretation using protein/polymer spectroscopic, calorimetric or particle sizing techniques (E.g., UV-Vis, Fluorescence, Circular Dichroism spectroscopy, DLS, HIAC, DSC, etc.)
• Proficiency with one or more data analysis software platforms (E.g., Excel, Prism, SigmaPlot, etc.).

Visa Sponsorship:

No

Agency / Institute:

NIH/NIAID