Translational Scientist
Apply NowCompany: International AIDS Vaccine Initiative
Location: La Jolla, CA 92037
Description:
As an organization whose mission is to translate science into global public health impact , working on vaccines and therapeutics, IAVI has a vaccine policy which states that subject to applicable law, we require all U.S. and Puerto Rico based employees to be vaccinated for COVID-19, unless they have an approved medical or religious exemption or accommodation. We are committed to supporting our employees during this process as we work to ensure a safe and healthy work environment.
Position Description
Title: Translational Scientist
Location: Neutralizing Antibody Center, Scripps Research, La Jolla, CA
Position Summary:
IAVI is seeking a dedicated Translational Scientist who will work closely with the SPR group to perform biochemistry lab techniques in the Neutralizing Antibody Center (NAC) lab. This position will be responsible for collaborating with other lab members to study HIV broadly neutralizing antibodies and the design of immunogens to elicit these antibodies through vaccination. This position will be based at the California campus of Scripps Research in La Jolla, CA, which offers access to broad range of research conducted on site, interaction with renowned scientists, seminar series, society of fellows and exposure to a scientific environment with state of the art equipment.
Key Responsibilities:
Education and Work Experience:
Qualifications and Skills:
ORGANIZATIONAL OVERVIEW:
IAVI is a nonprofit scientific research organization dedicated to addressing urgent, unmet global health challenges including HIV and tuberculosis. Our mission is to translate scientific discoveries into affordable, globally accessible public health solutions. Through scientific and clinical research in Africa, India, Europe, and the U.S., IAVI is pioneering the development of biomedical innovations designed for broad global access. We develop vaccines and antibodies in and for the developing world and seek to accelerate their introduction in low-income countries. IAVI programs and partnerships are grounded in the regions of the world where the disease burden is the greatest, and our approach emphasizes sustainability. Our network of clinical research center partners in Africa and India helps strengthen in-country research capacity and supports the training and education of the next generation of scientists. The global impact of our science includes fundamental contributions to understanding the biology of HIV infection, which IAVI and others are applying toward advancing vaccine science and immunology. IAVI accelerates scientific discovery and development by fostering unique collaborations among academia, industry, local communities, governments, and funders to explore new and better ways to address public health threats that disproportionately affect people living in poverty. Our global reach, including a clinical research network in five countries in sub-Saharan Africa and in India, has allowed us to make fundamental contributions to understanding the epidemiology, transmission, virology, and immunology of HIV. This work played a key role in facilitating the design of promising HIV vaccine candidates, as well as the discovery of broadly neutralizing antibodies that are now being advanced as promising approaches for HIV prevention. Our integrated capabilities in vaccine and antibody discovery, development, and clinical research take advantage of bio-pharmaceutical industry expertise to accelerate the development and testing of prevention methods for HIV and other diseases. Through the Product Development Center, we support external researchers with technical and scientific expertise to accelerate the development of their own products.
IAVI CORE VALUES:
Disclaimer: Nothing in this job description restricts management's right to assign or reassign duties and responsibilities to this job at any time. The above statements are intended to describe the general nature and level of work being performed by individuals assigned to this position. They are not intended to be an exhaustive list of all duties, responsibilities and skills required of personnel so classified. This document does not create an employment contract, implied or otherwise, other than an "at-will" relationship. IAVI is an equal opportunity employer and applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
IAVI IS AN EQUAL OPPORTUNITY EMPLOYER actively committed to fostering a diverse and inclusive global organization. IAVI believes that diversity and inclusion among our teammates is critical, and we seek to recruit, develop and retain the most talented people from a representative candidate pool. At IAVI, we celebrate the spectrum of colleagues' experiences and believe that dedication to our mission above all is essential to our success as a scientific global non-profit. IAVI upholds these principles through IAVI's Global Diversity and Inclusion Committee.
IAVI has zero tolerance for discrimination or harassment on the basis of race, color, ethnicity, caste, national origin, home language, ancestry, religion, marital or civil partnership status, age, physical or mental disability, HIV status and any other medical condition, genetic information, pregnancy, sexual orientation, gender identity or expression, and veteran status, in addition to any other status protected under the law in any of our locations worldwide
Position Description
Title: Translational Scientist
Location: Neutralizing Antibody Center, Scripps Research, La Jolla, CA
Position Summary:
IAVI is seeking a dedicated Translational Scientist who will work closely with the SPR group to perform biochemistry lab techniques in the Neutralizing Antibody Center (NAC) lab. This position will be responsible for collaborating with other lab members to study HIV broadly neutralizing antibodies and the design of immunogens to elicit these antibodies through vaccination. This position will be based at the California campus of Scripps Research in La Jolla, CA, which offers access to broad range of research conducted on site, interaction with renowned scientists, seminar series, society of fellows and exposure to a scientific environment with state of the art equipment.
Key Responsibilities:
- Perform biochemistry laboratory techniques to prepare samples and conduct experiments utilizing SPR and other biosensor-based instruments.
- Perform protein biochemistry and flow cytometry techniques to assess protein quality and stability in support of clinical trials.
- Work closely with the SPR group lead to establish priorities, develop protocols, verify results and further develop automation capabilities.
- Organize samples for parallel processing on multiple automated biosensor instruments, as well as maintain accurate records of sample amounts in the laboratory inventory database.
- Collaborate closely with other lab members to maximize instrument throughput.
- Utilize software programs (i.e., Microsoft Excel or Google Docs) and R-scripts to develop, optimize, and implement automated assays.
- Prepare reports documenting protein quality and stability for clinical trial reagents.
- Prepare reports that improve capabilities, efficiency, and productivity.
- Responsible for instrument maintenance, data quality control and ordering supplies, as necessary.
- Perform other tasks as assigned by manager.
Education and Work Experience:
- Bachelor's degree in Biochemistry, Biology, or a related field is required.
- Minimum 2 years of lab experience in protein biochemistry techniques is required; experience in SPR, Octet, high throughput or automated liquid handling, analytical assays, and/or protein and antibody purification and characterization is highly desirable.
Qualifications and Skills:
- Excellent track record of performing biochemistry laboratory techniques and preparing samples and conduct experiments is required,
- Thorough knowledge and experience utilizing SPR and other biosensor-based instruments are required.
- Ability to meet deadlines in a fast-paced, quickly changing environment is required.
- Ability to prioritize and organize a daily workload is required.
- Ability to work independently as well as collaboratively as a team member is required.
- Ability to troubleshoot and address technical hurdles is required.
- Excellent verbal and written communication skills is required.
- Strong work ethic and interpersonal skills is required.
ORGANIZATIONAL OVERVIEW:
IAVI is a nonprofit scientific research organization dedicated to addressing urgent, unmet global health challenges including HIV and tuberculosis. Our mission is to translate scientific discoveries into affordable, globally accessible public health solutions. Through scientific and clinical research in Africa, India, Europe, and the U.S., IAVI is pioneering the development of biomedical innovations designed for broad global access. We develop vaccines and antibodies in and for the developing world and seek to accelerate their introduction in low-income countries. IAVI programs and partnerships are grounded in the regions of the world where the disease burden is the greatest, and our approach emphasizes sustainability. Our network of clinical research center partners in Africa and India helps strengthen in-country research capacity and supports the training and education of the next generation of scientists. The global impact of our science includes fundamental contributions to understanding the biology of HIV infection, which IAVI and others are applying toward advancing vaccine science and immunology. IAVI accelerates scientific discovery and development by fostering unique collaborations among academia, industry, local communities, governments, and funders to explore new and better ways to address public health threats that disproportionately affect people living in poverty. Our global reach, including a clinical research network in five countries in sub-Saharan Africa and in India, has allowed us to make fundamental contributions to understanding the epidemiology, transmission, virology, and immunology of HIV. This work played a key role in facilitating the design of promising HIV vaccine candidates, as well as the discovery of broadly neutralizing antibodies that are now being advanced as promising approaches for HIV prevention. Our integrated capabilities in vaccine and antibody discovery, development, and clinical research take advantage of bio-pharmaceutical industry expertise to accelerate the development and testing of prevention methods for HIV and other diseases. Through the Product Development Center, we support external researchers with technical and scientific expertise to accelerate the development of their own products.
IAVI CORE VALUES:
- Dedication to the Mission: We are committed to the translation of scientific discoveries into affordable, globally accessible public health solutions.
- Innovative Evolution: We are committed to solving complex problems in creative and innovative ways, learning from our mistakes and successes and never giving up
- Integrity: We are committed to meeting the highest ethical and professional standards in everything we do and to taking responsibility for our actions to earn respect
- Collaboration: We are committed to embracing diversity, the power of global teamwork and the belief that by working as one we can make a difference
Disclaimer: Nothing in this job description restricts management's right to assign or reassign duties and responsibilities to this job at any time. The above statements are intended to describe the general nature and level of work being performed by individuals assigned to this position. They are not intended to be an exhaustive list of all duties, responsibilities and skills required of personnel so classified. This document does not create an employment contract, implied or otherwise, other than an "at-will" relationship. IAVI is an equal opportunity employer and applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
IAVI IS AN EQUAL OPPORTUNITY EMPLOYER actively committed to fostering a diverse and inclusive global organization. IAVI believes that diversity and inclusion among our teammates is critical, and we seek to recruit, develop and retain the most talented people from a representative candidate pool. At IAVI, we celebrate the spectrum of colleagues' experiences and believe that dedication to our mission above all is essential to our success as a scientific global non-profit. IAVI upholds these principles through IAVI's Global Diversity and Inclusion Committee.
IAVI has zero tolerance for discrimination or harassment on the basis of race, color, ethnicity, caste, national origin, home language, ancestry, religion, marital or civil partnership status, age, physical or mental disability, HIV status and any other medical condition, genetic information, pregnancy, sexual orientation, gender identity or expression, and veteran status, in addition to any other status protected under the law in any of our locations worldwide