RESEARCH SCIENTIST/ENGINEER 3
Apply NowCompany: University of Washington
Location: Seattle, WA 98115
Description:
As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem-solving skills, and dedication to build stronger minds and a healthier world.
UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits, and natural beauty.
The Division of Metabolism, Endocrinology and Nutrition (MET) has an outstanding opportunity for a Research Scientist/Engineer 3 to join their team.
POSITION PURPOSE
The Division of Metabolism, Endocrinology and Nutrition (MET) has an outstanding opportunity for a Research Scientist/Engineer 3 position to support studies within the Valencia Laboratory. Housed within the University of Washington Medicine Diabetes Institute at the South Lake Union campus, the Valencia laboratory's field of research is in the field of mitochondrial metabolism.
The purpose of the research this position supports, is to investigate how mitochondrial function adapts in response to obesity and weight loss and aging, and how these adaptations mediate cardiometabolic risk. Work will be done in one or two different labs within the UW SLU.
DUTIES AND RESPONSIBILITIES
The major duties of this position include running experiments for multiple projects using high-resolution fluo-respirometry to assess mitochondrial function in human and animal tissues and cell lines. This advanced, highly specialized position requires strong problem-solving skills and the ability to develop improved and more effective technical methodologies. The work is conducted independently, with only minor oversight. Additional duties include data collection and statistical analysis, tissue dissections, cell culture, processing of cells and tissues for respirometry, managing animal dietary experiments, and handling the performance of routine biological assays. Furthermore, this position requires proper coordination with our collaborators in shared projects. In addition to the recording, collection, organization, analysis and interpretation of data, this position will also have some administrative responsibilities and will contribute to presentations, manuscripts, and grants.
EXPERIMENTAL PROCEDURES (80%)
High-resolution respirometry of human and rodent tissues/cells.
Processing samples for high-resolution respirometry.
Rodent tissue dissection.
Microdissection of tissue for permeabilization (i.e. permeabilized fiber preparation).
Isolation of peripheral mononuclear cells from human blood.
Enzymatic assays, protein assay, ELISAS.
Western blotting and RT-PCR.
Record, collect, organize, analyze, interpret, and present data.
Analyzing data using statistical analysis software (STATA, R, Prism) and preparing figures.
ANIMAL MANAGEMENT (15%)
Weighing and feeding animals for dietary studies and keeping organized records.
Euthanizing animals for tissue harvest.
Organizing tissue harvests (tools, tubes, storage, etc.).
OTHER DUTIES (5%)
Training lab volunteers.
Editing and contributing to manuscripts or grants.
RESEARCH STAKEHOLDERS: NIH
MINIMUM REQUIREMENTS
Bachelor's degree in biological sciences or related field AND 4 years work related experience in the field of mitochondrial metabolism OR Equivalent combination of education/experience.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
ADDITIONAL REQUIREMENTS
Experience with assays of mitochondrial metabolism, specifically high resolution respirometry and enzymatic assays.
Experience isolating cells from human blood. Experience handling mice and performing rodent microdissection.
Experience with performing basic wet laboratory standard procedures.
Experience with statistical analysis.
Experience with data collection, recording and organization of data for graphical tabular presentation.
DESIRED QUALIFICATIONS
Prior experience with behavioral and physical measurements in animals.
Prior experience working in a wet laboratory.
Prior experience in team environment lab.
Application Process: The application process may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select "Apply to this position". Once you begin an assessment, it must be completed at that time; if you do not complete the assessment, you will be prompted to do so the next time you access your "My Jobs" page. If you select to take it later, it will appear on your "My Jobs" page to take when you are access ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
#UWDeptMedicineJobs
Committed to attracting and retaining a diverse staff, the University of Washington will honor your experiences, perspectives and unique identity. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable and welcoming.
The University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.
To request disability accommodation in the application process, contact the Disability Services Office at [redacted] or [redacted].
Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law.
UW faculty and staff also enjoy outstanding benefits, professional growth opportunities and unique resources in an environment noted for diversity, intellectual excitement, artistic pursuits, and natural beauty.
The Division of Metabolism, Endocrinology and Nutrition (MET) has an outstanding opportunity for a Research Scientist/Engineer 3 to join their team.
POSITION PURPOSE
The Division of Metabolism, Endocrinology and Nutrition (MET) has an outstanding opportunity for a Research Scientist/Engineer 3 position to support studies within the Valencia Laboratory. Housed within the University of Washington Medicine Diabetes Institute at the South Lake Union campus, the Valencia laboratory's field of research is in the field of mitochondrial metabolism.
The purpose of the research this position supports, is to investigate how mitochondrial function adapts in response to obesity and weight loss and aging, and how these adaptations mediate cardiometabolic risk. Work will be done in one or two different labs within the UW SLU.
DUTIES AND RESPONSIBILITIES
The major duties of this position include running experiments for multiple projects using high-resolution fluo-respirometry to assess mitochondrial function in human and animal tissues and cell lines. This advanced, highly specialized position requires strong problem-solving skills and the ability to develop improved and more effective technical methodologies. The work is conducted independently, with only minor oversight. Additional duties include data collection and statistical analysis, tissue dissections, cell culture, processing of cells and tissues for respirometry, managing animal dietary experiments, and handling the performance of routine biological assays. Furthermore, this position requires proper coordination with our collaborators in shared projects. In addition to the recording, collection, organization, analysis and interpretation of data, this position will also have some administrative responsibilities and will contribute to presentations, manuscripts, and grants.
EXPERIMENTAL PROCEDURES (80%)
ANIMAL MANAGEMENT (15%)
OTHER DUTIES (5%)
RESEARCH STAKEHOLDERS: NIH
MINIMUM REQUIREMENTS
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
ADDITIONAL REQUIREMENTS
DESIRED QUALIFICATIONS
Application Process: The application process may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Work Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select "Apply to this position". Once you begin an assessment, it must be completed at that time; if you do not complete the assessment, you will be prompted to do so the next time you access your "My Jobs" page. If you select to take it later, it will appear on your "My Jobs" page to take when you are access ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
#UWDeptMedicineJobs
Committed to attracting and retaining a diverse staff, the University of Washington will honor your experiences, perspectives and unique identity. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable and welcoming.
The University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.
To request disability accommodation in the application process, contact the Disability Services Office at [redacted] or [redacted].
Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law.