Translational Research Scientist - II
Apply NowCompany: Intelliswift
Location: South San Francisco, CA 94080
Description:
Job ID: 25-07371
Qualifications:
Required Experience and Skills:
B.S with minimum 5+ years'; Masters with 3+ years'; PHD with 1-2 years' of relevant work experience in industry or academia
Experience with immunohistochemistry and multiplexed immunofluorescence assay development
Experience using digital image analysis software and spatial imaging platforms such as HALO, Visiopharm, QuPath, digital slide scanning, multiplex spectral imaging, Akoya Polaris, Phenocycler/Fusion.
Strong organizational abilities and communication skills
Preferred Experience and Skills:
High level of comfort with histology/microanatomy strongly preferred
Background in oncology and/or immunology
Programming skills with application in imaging (e.g. Python, MATLAB) data
Experience with version control environments, such as Git
Experience with high-performance Linux cluster and cloud computing
Familiarity with client--servers and cloud computing infrastructure
The Successful Candidate will:
Perform validation and quality check of the analysis readout on multiplexed immunofluorescence images
Perform image preprocessing tasks according to established SOPs, including metadata extraction, output quality control, and secure data transfer to cloud storage.
Assist in evaluating and implementing new algorithms to enhance the image analysis pipeline, such as cell segmentation improvements, tissue classification, and cell phenotyping.
Assist with the transfer of data and image-related information for analysis, facilitating smooth collaboration between teams.
Coordinating with IT to
o Gather and document feedback from users on image analysis workflows and tools.
o Address user pain points, define requirements, and improve tool functionality.
o Lead user experience testing, working with IT to implement improvements and optimize tools for production use
o Maintain and update image analysis computers to ensure they remain optimized for routine tasks
Define and document requirements for new tools and ensure their successful deployment.
Provide administrative support for multiplex IHC related work, including reagent ordering, capital equipment purchasing, document and maintain SOPs for image processing and analysis workflows.
Interact smoothly with scientists, computer scientists, and informatics/IT staff, both internally and externally
Qualifications:
Required Experience and Skills:
B.S with minimum 5+ years'; Masters with 3+ years'; PHD with 1-2 years' of relevant work experience in industry or academia
Experience with immunohistochemistry and multiplexed immunofluorescence assay development
Experience using digital image analysis software and spatial imaging platforms such as HALO, Visiopharm, QuPath, digital slide scanning, multiplex spectral imaging, Akoya Polaris, Phenocycler/Fusion.
Strong organizational abilities and communication skills
Preferred Experience and Skills:
High level of comfort with histology/microanatomy strongly preferred
Background in oncology and/or immunology
Programming skills with application in imaging (e.g. Python, MATLAB) data
Experience with version control environments, such as Git
Experience with high-performance Linux cluster and cloud computing
Familiarity with client--servers and cloud computing infrastructure
The Successful Candidate will:
Perform validation and quality check of the analysis readout on multiplexed immunofluorescence images
Perform image preprocessing tasks according to established SOPs, including metadata extraction, output quality control, and secure data transfer to cloud storage.
Assist in evaluating and implementing new algorithms to enhance the image analysis pipeline, such as cell segmentation improvements, tissue classification, and cell phenotyping.
Assist with the transfer of data and image-related information for analysis, facilitating smooth collaboration between teams.
Coordinating with IT to
o Gather and document feedback from users on image analysis workflows and tools.
o Address user pain points, define requirements, and improve tool functionality.
o Lead user experience testing, working with IT to implement improvements and optimize tools for production use
o Maintain and update image analysis computers to ensure they remain optimized for routine tasks
Define and document requirements for new tools and ensure their successful deployment.
Provide administrative support for multiplex IHC related work, including reagent ordering, capital equipment purchasing, document and maintain SOPs for image processing and analysis workflows.
Interact smoothly with scientists, computer scientists, and informatics/IT staff, both internally and externally