Chief of Staff

Nearly all disease will become treatable in our lifetimes. At the same time, drug discovery is quickly becoming an engineering discipline. There has never been a more exciting time for new biotech research to solve humanity's most fundamental problems.

At Mandolin, we're building the "last mile" delivery infrastructure to accelerate this unbounded future of cutting-edge drugs - cell/gene therapies and biologics for Alzheimer's, cancer, schizophrenia, genetic disorders, amongst many others. Reasoning-adept LLMs uniquely unlock the opportunity to bridge this market gap. We're starting with an "AI knowledge worker" for clinics administering these drugs, and then partnering with health insurers and pharma companies to bring drug breakthroughs to market at scale.

Ultimately, our mission is to substantially extend healthy human lifespans by minimizing the time it takes to bring life-changing drugs to patients.

We're a lean, aggressive team of former founders set on building a new generational incumbent in healthcare. We've raised substantial institutional funding from the best healthcare AI investors like SignalFire, Maverick, and ex-Thrive GP Gaurav Ahuja (including first institutional checks into rocketships like Hims&Hers, Ro, Grow Therapy, Cityblock, and Devoted Health).

Mandolin was founded by Will Yin and Rohit Rustagi - Stanford dropouts and second-time exited founders - alongside teammates from Google, Stanford, Genentech, and others.

Why work at Mandolin?

We've found market fit and are building out our founding team very quickly. Reasons to join:

• We have incredible market pull and are already working closely with some of the largest healthcare providers all over the country.
• We're solving a difficult technical problem, which unlocks a massive $30B+ market opportunity and enormous impact once solved.
• You'll get to define the future of the company from the ground floor, alongside a world-class team from Stanford, Google, and Palantir.
• We are building an in-office culture in SF, while still being able to hire the best talent from anywhere. We will offer relocation to accommodate our in-office culture.

Who we're looking for

You'd be a perfect fit for our team if you...

• Thrive in the 0-to-1 phase, bringing ideas from concept to reality with a strong sense of ownership.
• Are passionate about creating reliable, scalable, and efficient infrastructure for cutting-edge systems.
• Are relentlessly truth-seeking in technical solutions, product needs, and business goals.
• Are opinionated yet open to collaboration, balancing best practices with practicality.
• Have a passion for building elegant, robust systems and a knack for solving problems both at a high level and in the details.

What you'll work on

As Chief of Staff at Mandolin, you'll be at the intersection of strategy, operations, and execution, playing a critical role in driving growth and efficiency. You'll work closely with cross-functional teams to identify opportunities, solve complex problems, and ensure the business operates seamlessly. Specific responsibilities include:

• Defining and driving key strategic initiatives to support product and business goals.
• Partnering with leadership to outline the 0-to-1 of projects, including requirements, goals, and roadmaps.
• Conducting data analysis and building models to inform decision-making across product, operations, and customer strategy.
• Designing and implementing scalable processes to optimize efficiency and drive operational excellence.
• Identifying and executing on opportunities to improve customer experience and unlock new revenue streams.
• Collaborating cross-functionally to solve challenges at the intersection of product, business, and operations.

Qualifications

• 3+ years of experience in business operations, strategy, management consulting, or a similar role.
• Strong analytical skills, with experience in data modeling and visualization tools like Excel, SQL, or Tableau.
• A proven track record of managing complex projects and delivering results in fast-paced environments.
• Excellent communication skills, with the ability to distill complex information into actionable insights.
• A strong intuition for balancing product, business, and technical tradeoffs.
• Experience with startups or building 0-to-1 systems and processes is highly desirable.

If this sounds awesome, send us a note at hiring@mandolin.com.