Biologist - Neurodegeneration

Job Details

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Eli Lilly and Company seeks a highly motivated scientist to join our Neurodegeneration team. This position is a part of a multidisciplinary team dedicated to discovering novel medicines for the treatment of Alzheimer's disease, Parkinson's disease, ALS, and other related neurodegenerative conditions. The individual will apply cutting-edge histological and imaging techniques to support our expanding neurodegeneration portfolio. A primary focus of this position will be the establishment and utilization of imaging/histological techniques to support therapeutic investigations in multiple pre-clinical animal models.

Key Objectives/Deliverables:

• Perform histological lab techniques including, but not limited to tissue processing, paraffin embedding, tissue sectioning, routine and special tissue staining, imaging and image analysis.
• Establish and execute multiplexed immunohistochemistry (IHC) and in situ hybridization (RNAScope) to evaluate in vivo efficacy of therapeutic agents
• Contribute to development, validation, and performing advanced histological/imaging techniques like spatial transcriptomics, super-resolution microscopy, light sheet microscopy and in vivo two photon imaging
• Assist in troubleshoot technical challenges and provide scientific/technical input to project teams
• Design, execute experiments and perform data analysis
• Communicate results to the project team to drive data-driven decisions
• Provide written and verbal communication of work in lab reports and team meetings
• Accurate recording of all practical work: completion of electronic notebook to Lilly procedure quality standards
• General laboratory assistance, including ordering and receiving lab supplies, preparation of reagents, and maintain laboratory equipment
• Ensure compliance with all health and safety regulations
• Report on-site, in the lab, 5 days a week

Basic Requirements:

• Bachelors degree in Neuroscience, biological sciences or related scientific fields
• Academic or industry experience with histologic analysis of animal models

Additional Skills/Preferences:

• Previous experience in neuroscience research is preferred
• Hands-on experience in autostainer (e.g. Leica Bond-RX), slide scanner imaging (e.g. Olympus VS200)
• Knowledge of relevant image analysis software packages: HALO, QuPATH and ImageJ
• Experience in stereotactic surgery and in vivo imaging is a plus
• Hands-on experience in cDNA library preparation for transcriptomics is a plus
• Ability to design, execute and interpret experiments independently
• Excellent communication skills and efficiency in collaborating across functional team
• Strong organization skills, attention to detail, critical thinking, multitasking, desire to learn new techniques and contribute to cutting-edge projects in a fast-paced working environment

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$63,000 - $162,800

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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