Sr Mgr, CMC Cell Culture Manufacturing

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Company: CSG International

Location: South San Francisco, CA 94080

Description:

Senior Manager, CMC - Cell Culture Manufacturing
Remote - PST Time Zone Preferred

An innovative, clinical-stage biotech company is hiring a Senior Manager, CMC - Cell Culture Manufacturing to oversee cell culture operations at CDMO partners supporting investigational antibody therapeutics. This fully remote position (PST preferred) offers the opportunity to make a tangible impact on both clinical development and future commercial scale-up efforts.

Key Responsibilities
  • Provide technical oversight for CDMOs manufacturing investigational biologics.
  • Evaluate and guide cell culture processes, including parameter specification and optimization.
  • Manage change controls, deviations, and CAPAs internally.
  • Review batch records, monitor data trends, and assess OOT/OOS results.
  • Draft and review protocols, technical reports, and risk assessments.
  • Contribute to regulatory filings (BLA/MAA), supporting CMC documentation.
  • Collaborate with cross-functional teams and participate in CDMO selection and onboarding.

Qualifications
  • Degree in Chemical Engineering, Bioengineering, Biology, Biochemistry, or related field (BS/MS/PhD).
  • 8+ years of biopharma experience, including product launch and process validation (PPQ).
  • Hands-on CDMO oversight experience in a cGMP environment.
  • Strong understanding of FDA and EU regulatory requirements.
  • Proven ability to work independently and drive projects forward.
  • Effective communicator with strong project management skills.
  • Willingness to travel occasionally for onsite meetings and PIP activities.

Why Apply?
Work with a purpose-driven team focused on advancing transformative antibody therapies. Enjoy the flexibility of a remote role while playing a critical role in shaping CMC strategy and execution.

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