Project Scientist Position in Digestive Diseases - Singh Lab 2025-2026
Apply NowCompany: University of California Los Angeles
Location: Los Angeles, CA 90011
Description:
Position description
The Division of Digestive Diseases in the Department of Medicine at the David Geffen School of Medicine at UCLA are seeking an advanced researcher at the Full Project Scientist level with extensive experience in autophagy-related research in mammalian liver. This individual must have completed 5 years of postdoctoral research and acquired an additional 5 year research experience in the field on autophagy with a deep understanding of the different forms of autophagy and how these relate to hepatic pathophysiology. The individual is expected to creatively initiate a program that studies distinct autophagic mechanisms into the regulation of hepatic lipid metabolism with a focus of metabolic dysfunction-associated steatotic liver disease and its progression. This candidate must be experienced with methods including and not limited to isolation of various autophagic, lysosome and late endosomal, and lipid droplet fractions from mouse livers using density gradient centrifugation, and use of Seahorse Respirometry to determine hepatic energetic states. The candidate must also be able to analyze and interpret said data and use these to generate new ideas and hypotheses to move the project/field forward. The project will focus on identifying new mechanisms leading to defects in lysosomal fat droplet turnover. The candidate will report to Dr. Rajat Singh and will have access to all of the resources and reagents in the Singh lab to accomplish the work. A Ph.D. is required.
The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what's right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at https://medschool.ucla.edu/cultural-north-star
Qualifications
Basic qualifications
A Ph.D. is required.
Additional qualifications
Candidate must have completed 5 years of postdoctoral research and acquired an additional 5 year research experience in the field on autophagy with a deep understanding of the different forms of autophagy and how these relate to hepatic pathophysiology.
Application Requirements
Document requirements
Reference requirements
None
Apply link: https://recruit.apo.ucla.edu/JPF10276
Help contact: jmavelar@mednet.ucla.edu
About UCLA
As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
For the University of California's Affirmative Action Policy, please visit https://www.ucop.edu/academic-personnel-programs/_files/apm/apm-035.pdf .
For the University of California's Anti-Discrimination Policy, please visit https://policy.ucop.edu/doc/1001004/Anti-Discrimination .
As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct, are currently being investigated for misconduct, left a position during an investigation for alleged misconduct, or have filed an appeal with a previous employer.
Job location
Los Angeles, CA
The Division of Digestive Diseases in the Department of Medicine at the David Geffen School of Medicine at UCLA are seeking an advanced researcher at the Full Project Scientist level with extensive experience in autophagy-related research in mammalian liver. This individual must have completed 5 years of postdoctoral research and acquired an additional 5 year research experience in the field on autophagy with a deep understanding of the different forms of autophagy and how these relate to hepatic pathophysiology. The individual is expected to creatively initiate a program that studies distinct autophagic mechanisms into the regulation of hepatic lipid metabolism with a focus of metabolic dysfunction-associated steatotic liver disease and its progression. This candidate must be experienced with methods including and not limited to isolation of various autophagic, lysosome and late endosomal, and lipid droplet fractions from mouse livers using density gradient centrifugation, and use of Seahorse Respirometry to determine hepatic energetic states. The candidate must also be able to analyze and interpret said data and use these to generate new ideas and hypotheses to move the project/field forward. The project will focus on identifying new mechanisms leading to defects in lysosomal fat droplet turnover. The candidate will report to Dr. Rajat Singh and will have access to all of the resources and reagents in the Singh lab to accomplish the work. A Ph.D. is required.
The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what's right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at https://medschool.ucla.edu/cultural-north-star
Qualifications
Basic qualifications
A Ph.D. is required.
Additional qualifications
Candidate must have completed 5 years of postdoctoral research and acquired an additional 5 year research experience in the field on autophagy with a deep understanding of the different forms of autophagy and how these relate to hepatic pathophysiology.
Application Requirements
Document requirements
- Curriculum Vitae - Your most recently updated C.V.
Reference requirements
None
Apply link: https://recruit.apo.ucla.edu/JPF10276
Help contact: jmavelar@mednet.ucla.edu
About UCLA
As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
For the University of California's Affirmative Action Policy, please visit https://www.ucop.edu/academic-personnel-programs/_files/apm/apm-035.pdf .
For the University of California's Anti-Discrimination Policy, please visit https://policy.ucop.edu/doc/1001004/Anti-Discrimination .
As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct, are currently being investigated for misconduct, left a position during an investigation for alleged misconduct, or have filed an appeal with a previous employer.
- "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
- UC Sexual Violence and Sexual Harassment Policy
- UC Anti-Discrimination Policy for Employees, Students and Third Parties
- APM - 035: Affirmative Action and Nondiscrimination in Employment
Job location
Los Angeles, CA