Associate Scientist, Analytical Chemistry

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Company: Evercrisp Biosciences

Location: South San Francisco, CA 94080

Description:

Company Description
Evercrisp Biosciences, founded by world-renowned scientists with expertise in cutting-edge proprietary technologies, operates in stealth mode with substantial Series A backing from Apple Tree Partners (ATP). Evercrisp is focused on tackling genetically validated, "difficult-to-drug" targets, particularly in areas of high unmet need where genetic medicines can create transformative outcomes. At Evercrisp, innovation, collaboration, and a deep commitment to advancing human health drive our mission to develop first-in-class therapeutics.

Position Overview
Evercrisp Biosciences is seeking a highly skilled and motivated Associate Scientist to support our efforts in the discovery and development of next-generation genetic medicines. The ideal candidate will have a strong foundation in the purification and analytical characterization of complex bioconjugates and a desire to contribute to the development of novel drug delivery systems. This role offers a unique opportunity to contribute to innovative programs targeting challenging biology in areas of high unmet medical need.

Key Responsibilities

  • Lead the purification, formulation, and characterization of diverse bioconjugates to enable in vivo applications
  • Formulate and characterize Cas9 sgRNA complexes
  • Contribute to the development and execution of functional assays (e.g. activity assays, ELISA, qPCR, etc.) to study and evaluate test articles
  • Support material generation with basic bioconjugations
  • Maintain detailed and accurate records in Electronic Laboratory Notebooks (ELNs) to ensure data integrity and accessibility
  • Collaborate with other team members to problem-solve challenges quickly and efficiently as they arise

Qualifications

  • Bachelor's or Master's degree in Analytical Chemistry, Bioengineering, or a related field, with 5-8 years of hands-on laboratory experience.
  • Strong hands-on experience with relevant purification (SEC, TFF, RP, Affinity, IEX) and analytical methodologies (SEC-MALS, LCMS, ELISA, qPCR, etc.).
  • Ability to work collaboratively in a fast-paced, dynamic research environment.
  • Strong analytical, organizational, and communication skills.
  • A passion for innovation and the development of transformative genetic medicines.
  • Prior experience generating and characterizing protein bioconjugates in a drug discovery setting is preferred.
  • Prior experience with gene-editing platforms is preferred.

Skills and Attributes:
  • Strong attention to detail, accurate record-keeping, and adherence to lab best practices and safety protocols
  • Expertise in developing methods, optimizing protocols, and preparing technical documents
  • Independence in the execution of high quality, well-controlled experiments
  • Effective time management skills enabling multi-tasking across a diversity of initiatives and projects
  • Thrives in a dynamic, collaborative, and fast-paced team environment

What We Offer
At Evercrisp Biosciences, you'll be part of a passionate team working at the forefront of genetic medicine. We offer a competitive compensation package, comprehensive benefits, and the opportunity to grow professionally in a highly innovative environment.

At Evercrisp, we value diversity, encourage professional growth, and provide competitive benefits and compensation. Evercrisp is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

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