Scientist / Senior Scientist in Immunology

We are a well-funded biotech startup that has developed a proprietary single cell platform that resolves a bottleneck for immunotherapy. We are currently looking for a protein engineering scientist with experience in TCR affinity maturation and T cell engager (TCE) development to join our interdisciplinary team. The candidate is expected to adapt quickly and communicate well, especially in a fast-paced startup environment. He/she will collaborate with other team members and be part of an exciting journey. We pay competitive salaries with bonus and equity, plus full benefits that include medical, dental, vision, 401k match, commuter benefits and daily lunch.

Responsibilities:

• Design and perform TCR affinity maturation for enhanced affinity, specificity, and stability.
• Develop TCEs and conduct in vitro functional assays to assess efficacy and safety.
• Work with CRO to perform in vivo evaluations of lead TCEs.
• Collaborate cross-functionally with immunologists, computational scientists, and engineers to advance the TCE development efforts.

Skills and Qualifications:

• PhD in Biochemistry, Immunology, Molecular Biology, Bioengineering, or a related field, with 2+ years of postdoctoral or industry experience.
• Expertise in display technologies and high-throughput screening.
• Strong background in TCR engineering and TCE development.
• Hands-on experience with cell-based immune assays, such as flow cytometry, cytokine profiling, and cytotoxicity assays.
• Experience with mammalian expression systems and protein purification techniques is a plus.
• Expertise in structural biology is a plus.
• Ability to work in a fast-paced startup environment, take initiative, and drive projects forward independently.
• Excellent communication and collaboration skills.

Compensation and Benefits:

Compensation:

• $120,000 - $160,000 (depending on the depth of expertise) + 10% performance bonus + equity.

Benefits:

• 4% Salary 401K match; Daily lunches; Commuter Benefits; Unlimited snacks and drinks.
• Medical, Dental, Vision; 100% Premium Covered.
• Disability Insurance, Life Insurance; Workplace Insurance;