Senior Scientist I Functional Antibody Screening

Job Details

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on X , Facebook , Instagram , YouTube , LinkedIn and Tik Tok .

Job Description

Discovery Biotherapeutics and Genetic Medicine (BGM) at Abbvie is seeking a highly motivated research scientist to join the Cell and Functional Biology group at the Cambridge Research Center (CRC). The CRC site based in Cambridge, MA offers a unique setting where BGM, Immunology, Neuroscience, and Genomic Research Center co-exist. In this role, you will be responsible for the conceptualization and execution of cell- and protein- based functional characterization assays for lead antibody identification/optimization and collaborating to generate stage-gate appropriate in vitro / cellular / in vivo data packages supporting PoC. The ideal candidate should have strong experience with fluorescent reporters, fluorescent assay development, cell culture and antibody screening and significant experience in flow cytometry, cell-based assays and imaging. Familiarity with high-throughput screening and multi-specifics is highly valued. The applicant should be able to analyze, document, and report data. You should possess excellent communication skills and be comfortable working in cross-functional teams.

Job Responsibilities:

• Lead the development and implementation of cell-based fluorescent assays to enable function-first antibody screening across multiple therapeutic areas and drug discovery stages.
• Design, optimize, and validate assay protocols, ensuring robustness and reproducibility across projects.
• Analyze and interpret complex data sets, providing insights and recommendations for next steps in research projects.
• Stay abreast of technological advancements in cell-based assays, fluorescence applications, and imaging techniques to support the expansion of function-first assay design.
• Develop close cross-functional relationships with therapeutic area scientists to drive synthesis of innovative ideas and solutions to achieve organizational goals.
• Demonstrate scientific excellence through dedication to multiple projects in a fast-paced multi-disciplinary environment

Qualifications

Qualifications:

• BS with 10+ years of experience or MS with 8+ years of experience or PhD with no experience in Biology, Molecular and Cellular Biology, Biomedical Engineering, Immunology or other related field.
• Proficient in conceptualization and implementation of in vitro fluorescent plate-based assays.
• Expertise in cell-culture, flow cytometry, ELISA/microplate cytometry, luminescence and imaging platforms.
• Proficiency in data analysis and statistical software.
• Ability to work independently as well as part of a collaborative team environment.
• Strong attention to quality and details when exercising organizational, documentation and communication skills.

Desirable:

• Experience with high-throughput screening, programming and multi-specific antibodies.
• Experience with external collaborations and partnerships.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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