Medical Director, Hematopoetic Stemcell Transplantation-associated Thrombotic Microangiopathy

This is what you will do:

Reporting to the Executive Medical Director, Hematology & Nephrology, the Medical Affairs Director, HSCT-TMA, will contribute to strategic planning, tactical execution and leadership in hematopoetic stemmcell transplantation-associated thrombotic microangiopathy in the US Medical team, responsible for providing strong scientific and medical perspective with an in-depth understanding of the HSCT-TMA medical landscape. The incumbent will contribute to development and implementation of the short and long-term strategies for both inline and pipeline assets, aligning with overall Alexion organizational strategy and ensuring effective and meaningful cross-functional collaboration on the US level. Further, the Medical Director, HSCT-TMA, will work with relevant Global Medical counterparts and leadership to support the Alexion Global Medical Affairs mission to improve patient outcomes by setting and continuously advancing the evidence-based medical standard of care.

You will be responsible for:

In collaboration with the medical US and global as well as cross-functional colleagues, the Medical Director will develop and facilitate implementation of the medical (HSCT-TMA) strategic plan for USMA activities (pre-, peri- and post -launch as applicable) by providing medical leadership, insights and strategy to USMA team across functions.

Responsible for the following:

• Contributing to the development and implementation of the US strategy and plan for US MA activities for HSCT-TMA by providing medical leadership, insight and strategic guidance to the US HSCT-TMA medical team.
• Under the leadership and in collaboration with Executive Medical Director, providing medical strategic and tactical plans for late phase pipeline program for HSCT-TMA as well as future LCM and potential late phase pipeline programs in the therapeutic area.
• Leading the situational assessment of the patient journey and the US product strategy development including harmonization of activities involving KOLs cross-functionally.
• Developing in-year medical strategy and tactical plan for the US Medical Affairs team for HSCT-TMA
• Contributing scientific and medical acumen to registration programs working closely with GMA
• Providing medical review and assurance of alignment with HSCT-TMA strategic areas of interest for Investigator Sponsored Research (ISR) proposals.
• Providing medical guidance, as appropriate, regarding scientific communication, internal medical training, external medical education (CME, Symposia, medical education), Medical information.
• Contributing medical perspective to commercial strategy as appropriate
• Support TA lead with team's performance in terms of goals and delivery of US medical plans.
• Serving as a medical expert and resource within ALXN in support of the therapeutic area.
• Leading content development and presentation for external medical education programs and other medical initiatives.
• Developing, conducting, or contributing to therapeutic training programs for Alexion personnel.
• Establishing strategic partnerships with Centers of Excellence and KOLs in areas of scientific interest and serves as conduit for flow of information both out to the medical community and into the company.
• Working closely with the Field medical team in the development and execution of US KOL medical engagement strategy.
• Establishing and/or enhancing partnerships with key academic institutions and develop relationships with key thought leaders.
• Planning, designing and managing medical Advisory Boards and gather insight from national/regional/local medical Advisory Boards.

You will need to have:

• Must have an MD, PhD or PharmD level degree or equivalent- Hematology, Hematooncology (specifically Bonemarrow-Transplant), or Nephrology would be a plus.
• At least 3-5 years experience in Medical Affairs or other relevant industry functions.
• Experience/ability to work in a matrix cross-functional environment, both internally and remotely.
• Excellent English communication skills, both written and verbal.
• Team player with ability to inform and motivate a team, including remote personnel.
• Excellent interpersonal skills with demonstrated track record and ability to drive results as an effective team member and project leader.
• Proven ability to manage budget and resources.
• Strong scientific, clinical and business acumen.
• Flexibility and ability to adapt to changing environment.
• Excellent problem solving, organizational, and negotiating skills.
• Must demonstrate an energy and enthusiasm which brings a positive approach to all challenges.
• Strong sense of ethics and integrity. Strong working knowledge of US regulatory environment.
• Travel required up to 25%.
• The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.
• The role is located in Boston/MA

Date Posted
17-Apr-2025

Closing Date
05-Jun-2025Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact accommodations@Alexion.com. Alexion participates in E-Verify.